1-氯-2-甲基-2-苯基丙烷合成路线 （共 56 条）
反应条件
1.1: 1-methyl-pyrrolidin-2-one / 160 - 165 °C 2.1: AlCl3, aluminium chloride / dichloromethane / 0 - 5 °C / Inert atmosphere 2.2: 0 °C / Inert atmosphere View Scheme
参考文献
Jubilant Organosys Limited
Patent: EP2289867 A2, 2011 ;
反应条件
1.1: 1-methyl-pyrrolidin-2-one / 160 - 165 °C 2.1: AlCl3, aluminium chloride / dichloromethane / 0 - 5 °C / Inert atmosphere 2.2: 0 °C / Inert atmosphere 3.1: sodium hydroxide; methanol / 2 h / 20 °C 4.1: potassium permanganate; acetic acid / water; acetone / 0 - 20 °C View Scheme
参考文献
Jubilant Organosys Limited
Patent: EP2289867 A2, 2011 ;
反应条件
in tetrahydrofuran; diethyl ether
T=0°C; Schlenk technique;
参考文献
Dobereiner, Graham E.; Yuan, Jian; Schrock, Richard R.; Goldman, Alan S.; Hackenberg, Jason D.
Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12572 - 12575
反应条件
(i) Mg, BrCH2CH2Br, Et2O, (ii) Br2; Multistep reaction;
参考文献
Ferkous, Fouad; Degueil-Castaing, Marie; Deleuze, Herve; Maillard, Bernard
Journal of the Chemical Society Perkin Transactions 2, 2002 , vol. 2, p. 247 - 250
反应条件
aluminium trichloride in benzene
T=21 - 22°C;
参考文献
Bruson,H.A.; Plant,H.L.
Journal of Organic Chemistry, 1967 , vol. 32, p. 3356 - 3362
反应条件
in 1-methyl-pyrrolidin-2-one
T=160 - 165°C;
参考文献
Jubilant Organosys Limited
Patent: EP2289867 A2, 2011 ;
Location in patent: Page/Page column 7 ;
参考文献
Whitmore; Weisgerber; Shabica
Journal of the American Chemical Society, 1943 , vol. 65, p. 1469
参考文献
Whitmore; Weisgerber; Shabica
Journal of the American Chemical Society, 1943 , vol. 65, p. 1469
参考文献
Whitmore; Weisgerber; Shabica
Journal of the American Chemical Society, 1943 , vol. 65, p. 1469
参考文献
Haller; Ramart
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1922 , vol. 174, p. 1212
