1: 62 percent / DBU / various solvent(s) / 48 h 2: 68 percent / sodium azide, ammonium chloride / dimethylformamide / 1.2 h / Heating 3: 1.) 1.4 M methanolic hydrochloric acid / 1.) reflux, 1.5 h; 2.) pyridine, roomtemp., overnight 4: 82 percent / barium hydroxide octahydrate / methanol / 0.17 h / Ambient temperature 5: 79 percent / H2 / Pd-black / H2O / 1 h View Scheme

methanol; ammonia T=110°C;

1: With sodium methylate T=20°C; 3 h; 2: With hydrogenchloride 0.5 h; Heating; Further stages.;

sodium methylate T=20°C; 4 h;

1: NaN3 / methanol / 4 h / 85 °C 2: 1.) PPh3, 2.) conc. NH4OH / 1.) DMF, r.t., 2 h, 2.) r.t., 20 h View Scheme

1: sodium azide / N,N-dimethyl-formamide 2: sodium methylate / methanol 3: hydrogen / methanol View Scheme