2-氯-3-氰基-6-甲氧基-4-甲基l吡啶合成路线 （共 3 条）
反应条件
1: in methanol
T=20°C; 3 h;
2: With hydrogenchloride in methanol; water
pH=6 - 7;
参考文献
SK CHEMICALS, CO., LTD.
Patent: WO2005/63768 A1, 2005 ;
Location in patent: Page/Page column 65-66 ;
反应条件
1: methyl (2,6-dichloro-3-{[methyl(pent-4-enyl)amino]carbonyl}pyridin-4-yl)acetate With potassium hydroxide; water in methanol
T=20°C; Hydrolysis; 12 h;
2: diazomethane Methylation;
参考文献
Sarkar, Tarun K.; Basak, Sankar; Ghosh, Sunil K.
Tetrahedron Letters, 2000 , vol. 41, # 5 p. 759 - 762
反应条件
in methanol
T=20 - 40°C; 0.5 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Pelisson, Marcelo M. M.; Da Silva, Gil Valdo Jose; Clive, Derrick L. J.; Coltart, Don M.; Hof, Fraser A.
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 653 - 658
