1H-萘嵌间二氮杂苯-2(3H)-酮合成路线 （共 19 条）
反应条件
potassium hydroxide in dimethyl sulfoxide 1.) room temp., 2.5 h; 2.) 100 deg C, 1 h.;
参考文献
Kurasov, L. A.; Posharskii, A. F.; Kuz'menko, V. V.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 1735 - 1738
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, p. 1944 - 1947
反应条件
trichlorophosphate 3 h; Heating;
参考文献
Herbert, John M.; Woodgate, Paul D.; Denny, William A.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 2081 - 2086
反应条件
in tetrahydrofuran; hexane; water
参考文献
LG Chem, Ltd.
Patent: EP1680479 B1, 2012 ;
参考文献
Sachs
Justus Liebigs Annalen der Chemie, 1909 , vol. 365, p. 162
反应条件
1: 79 percent / KOH / acetone / 1 h / Ambient temperature 2: 74 percent / sodium amide / various solvent(s) / 3 h / 170 - 190 °C View Scheme
参考文献
Konstantinchenko, A. A.; Pozharskii, A. A,; Stepanova, V. N.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 7.2 p. 1195 - 1199
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 7 p. 1437 - 1442
反应条件
N-methyl-pyrrolidine; selenium in tetrahydrofuran
T=100°C; P=22800.7 Torr; 20 h;
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Murai, Shinji; Sonoda, Noboru
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 1793 - 1800
反应条件
in tetrahydrofuran
T=25 - 40°C;
参考文献
Gong, Jiachang; Sturla, Shana J.
Journal of the American Chemical Society, 2007 , vol. 129, # 16 p. 4882 - 4883
反应条件
TBA2[WO4] in 1-methyl-pyrrolidin-2-one
T=139.84°C; P=15001.5 Torr; 24 h; Autoclave;
参考文献
Kimura, Toshihiro; Kamata, Keigo; Mizuno, Noritaka
Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6700 - 6703
参考文献
Herbert, John M.; Woodgate, Paul D.; Denny, William A.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 2081 - 2086
参考文献
Kim, Kong Kyeom; Lee, Min Jeong; Kim, Yeon Hwan; Jang, Jun Gi
Patent: US2005/123800 A1, 2005 ;
