1: 65 percent / p-toluenesulfonic acid / methanol / 18 h / 20 °C
2: 58 percent / K2HPO4; KH2PO4; NaBr / dimethylsulfoxide / 20 h / 80 °C
View Scheme
参考文献
Lambertin, Frederic; Wende, Martin; Quirin, Marie Jeanne; Taran, Martine; Delmond, Bernard
European Journal of Organic Chemistry, 1999 , # 6 p. 1489 - 1494
1.1: N-bromosuccinimide; water / acetone / 15 h / 20 °C
1.2: 7.36 g / NaH / dimethylformamide / 15 h / 0 - 20 °C
2.1: 79 percent / NaIO4 / H2O; 2-methyl-propan-2-ol / 15 h / 20 °C
3.1: t-BuOCl / 1 h / 0 °C
4.1: 14.8 g / CuSO4; H2SO4 / acetic acid / 96 h / 20 °C
5.1: 75 percent / Na2CO3; H2O / methanol / 5 h / 0 °C
6.1: 90 percent / pyridinium chlorochromate / CH2Cl2 / 1.5 h / 0 °C
7.1: 65 percent / p-toluenesulfonic acid / methanol / 18 h / 20 °C
8.1: 58 percent / K2HPO4; KH2PO4; NaBr / dimethylsulfoxide / 20 h / 80 °C
View Scheme
参考文献
Lambertin, Frederic; Wende, Martin; Quirin, Marie Jeanne; Taran, Martine; Delmond, Bernard
European Journal of Organic Chemistry, 1999 , # 6 p. 1489 - 1494
tetrakis(triphenylphosphine) palladium(0); potassium salt of 2-nitropropane in tert-butyl alcohol
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
