(R)-(−)-环氧氯丙烷合成路线 （共 62 条）
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water T=0 - 20°C;
参考文献
Schaus, Scott E.; Branalt, Jonas; Jacobsen, Eric N.
Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 4876 - 4877
反应条件
(S,S)-salen-Co(III)-OAc complex; H2O (dist.) T=0°C; 14 h;
参考文献
Larrow, Jay F.; Hemberger, Karl E.; Jasmin, Serge; Kabir, Hocine; Morel, Phillipe
Tetrahedron Asymmetry, 2003 , vol. 14, # 22 p. 3589 - 3592
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; (salen)Co(III)-AlCl3; water in tetrahydrofuran T=19.84°C; 3 h; Kinetics; Reagent/catalystSolvent; optical yield given as percent eeenantioselective reaction;
参考文献
Jiang, Chengjun
Kinetics and Catalysis, 2011 , vol. 52, # 5 p. 691 - 696
反应条件
ethylene glycol disodium salt in ethylene glycol 0.25 h; Ambient temperature;
参考文献
Chen, Ching-Shih; Liu, Yeuk-Chuen; Marsella, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 9 p. 2559 - 2561
反应条件
Agromyces mediolanus ZJB120203 epoxide hydrolase Resolution of racemate; enantioselective reaction;
参考文献
Xue, Feng; Liu, Zhi-Qiang; Zou, Shu-Ping; Wan, Nan-Wei; Zhu, Wen-Yuan; Zhu, Qing; Zheng, Yu-Guo
Process Biochemistry, 2014 , vol. 49, # 3 p. 409 - 417
反应条件
water T=20°C; 8 h; optical yield given as percent ee;
参考文献
Zheng, Xiaolai; Jones, Christopher W.; Weck, Marcus
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 2 p. 255 - 261
反应条件
potassium carbonate; Co(II)(3,5-Cl,Cl-sal)2(S-CHXDA) (e.e. 1.) 130-150 deg C, 3 hr in vacuo; 2.) CH2Cl2, 25 deg C, 6 days; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Li, Wenji; Thakur, Santosh Singh; Chen, Shu-Wei; Shin, Chang-Kyo; Kawthekar, Rahul B.; Kim, Geon-Joong
Tetrahedron Letters, 2006 , vol. 47, # 20 p. 3453 - 3457
反应条件
hydrogenchloride; tert-butyl methyl ether; dimeric chiral (salen)Co complex linked with Al in diethyl ether T=0 - 5°C; 2 h; Product distribution; Further Variations:Catalysts;
参考文献
Thakur, Santosh Singh; Li, Wenji; Kim, Seong-Jin; Kim, Geon-Joong
Tetrahedron Letters, 2005 , vol. 46, # 13 p. 2263 - 2266
反应条件
water; poly(Co(III)(OTs)-salen-norbornene) in chlorobenzene T=20°C; 0.5 h; Product distribution; Further Variations:Catalystsreaction times;
参考文献
Wezenberg, Sander J.; Kleij, Arjan W.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 1 p. 85 - 91
