(R)-(−)-环氧氯丙烷合成路线 （共 62 条）
反应条件
hydrogenchloride 24 h; Ambient temperature;
参考文献
Takle, Andrew; Kocienski, Philip
Tetrahedron, 1990 , vol. 46, # 13/14 p. 4503 - 4516
反应条件
tert.-butylhydroperoxide; Caldariomyces fumago chloroperoxidase T=20°C; pH=5.5; 1 h; aq. phosphate bufferIonic liquidEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Wu, Jinyue; Liu, Chen; Jiang, Yucheng; Hu, Mancheng; Li, Shuni; Zhai, Quanguo
Catalysis Communications, 2010 , vol. 11, # 8 p. 727 - 731
反应条件
sodium salt of ethane-1,2-dithiol in ethylene glycol 0.25 h; Yield given;
参考文献
Ellis, Martin K.; Golding, Bernard T.; Maude, Antony B.; Watson, William P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 4 p. 747 - 755
反应条件
monosodium salt of ethylene glycol in ethylene glycol 0.0833333 h; Title compound not separated from byproducts;
参考文献
Russel, Stephen W.; Pabon, Henk J. J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 545 - 552
反应条件
potassium carbonate in dichloromethane T=25°C; 144 h; study of asymmetric cyclization using optically active Co(II)(Sal)2(R-CHXDA) type catalyst; Product distributionMechanism;
参考文献
Takfichi, Tsutomu; Arihara, Motoji,; Ishimori, Michihiro; Tsuruta, Teiji
Tetrahedron, 1980 , vol. 36, p. 3391 - 3398
反应条件
hydrogen bromide; monosodium salt of ethylene glycol 1.) AcOH, 60 deg C, 5 h,; Yield given. Multistep reaction;
参考文献
Ellis, Martin K.; Golding, Bernard T.; Watson, William P.
Journal of the Chemical Society, Chemical Communications, 1984 , # 23 p. 1600 - 1602
反应条件
sodium azide; sodium acetate buffer; Agrobacterium radiobacter AD1 haloalcohol dehalogenase T=22°C; pH=4.5; Product distribution; Further Variations:pH-values;
参考文献
Lutje Spelberg, Jeffrey H.; Tang, Lixia; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 2004 , vol. 15, # 7 p. 1095 - 1102
反应条件
1: 4-Fluorophenyl alcohol With potassium carbonate in butanone T=20°C; 0.166667 h; Inert atmosphereSchlenk technique; 2: (R)-(-)-epichlorohydrin in butanone T=90°C; 15 h; Inert atmosphereSchlenk technique;
参考文献
Park, Jung-Eun; Ji, Wan Keun; Jang, Jae Wan; Pae, Ae Nim; Choi, Keehyun; Choi, Ki Hang; Kang, Jahyo; Roh, Eun Joo
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 6 p. 1887 - 1890
反应条件
caesium carbonate in acetonitrile Reflux;
参考文献
Sun, Dianqing; Scherman, Michael S.; Jones, Victoria; Hurdle, Julian G.; Woolhiser, Lisa K.; Knudson, Susan E.; Lenaerts, Anne J.; Slayden, Richard A.; McNeil, Michael R.; Lee, Richard E.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 10 p. 3588 - 3594
反应条件
[(R,R)-N,N-bis-(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-Co(III)-acetate]; water in tetrahydrofuran T=4°C; 24 h;
参考文献
Furrow, Michael E.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of Organic Chemistry, 1998 , vol. 63, # 20 p. 6776 - 6777
