1-(4-氟苯基)-2-丙烯-1-酮合成路线 （共 7 条）
反应条件
dihydrogen peroxide in tetrahydrofuran
T=0 - 20°C; 0.5 h;
参考文献
Tiwari, Praveen Kumar; Aidhen, Indrapal Singh
Synlett, 2013 , vol. 24, # 14 art. no. ST-2013-B0343-L, p. 1777 - 1780
反应条件
1.1: copper(ll) bromide / chloroform; ethyl acetate / 0.33 h / Reflux; Inert atmosphere
2.1: triethylamine / toluene / 20 °C
3.1: methanol; water / 1 h / 20 °C
3.2: 20 °C / pH 7 - 8
4.1: dichloromethane / Reflux; Inert atmosphere
View Scheme
参考文献
An, Xiao-Lei; Chen, Jia-Rong; Li, Chang-Feng; Zhang, Fu-Gen; Zou, You-Quan; Guo, Ying-Cen; Xiao, Wen-Jing
Chemistry - An Asian Journal, 2010 , vol. 5, # 10 p. 2258 - 2265
反应条件
1.1: triethylamine / toluene / 20 °C
2.1: methanol; water / 1 h / 20 °C
2.2: 20 °C / pH 7 - 8
3.1: dichloromethane / Reflux; Inert atmosphere
View Scheme
参考文献
An, Xiao-Lei; Chen, Jia-Rong; Li, Chang-Feng; Zhang, Fu-Gen; Zou, You-Quan; Guo, Ying-Cen; Xiao, Wen-Jing
Chemistry - An Asian Journal, 2010 , vol. 5, # 10 p. 2258 - 2265
反应条件
N-methylanilinium trifluoroacetate in tetrahydrofuran
10 h; Inert atmosphereReflux;
参考文献
Yang, Tang-Po; Li, Qiang; Lin, Jin-Hong; Xiao, Ji-Chang
Chemical Communications, 2014 , vol. 50, # 9 p. 1077 - 1079
反应条件
triethylamine in diethyl ether
3 h;
参考文献
Wilkerson; DeLucca; Galbraith; Gans; Harris; Jaffee; Kerr
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 7 p. 667 - 676
反应条件
in dichloromethane
RefluxInert atmosphere;
参考文献
An, Xiao-Lei; Chen, Jia-Rong; Li, Chang-Feng; Zhang, Fu-Gen; Zou, You-Quan; Guo, Ying-Cen; Xiao, Wen-Jing
Chemistry - An Asian Journal, 2010 , vol. 5, # 10 p. 2258 - 2265
反应条件
1.1: methanol; water / 1 h / 20 °C
1.2: 20 °C / pH 7 - 8
2.1: dichloromethane / Reflux; Inert atmosphere
View Scheme
参考文献
An, Xiao-Lei; Chen, Jia-Rong; Li, Chang-Feng; Zhang, Fu-Gen; Zou, You-Quan; Guo, Ying-Cen; Xiao, Wen-Jing
Chemistry - An Asian Journal, 2010 , vol. 5, # 10 p. 2258 - 2265
