反应条件
1: 1.) Li, NH3, 2.) 10percent HCl / 1.) t-butyl alcohol, THF, - 33 deg C, 5 h, 2.) MeOH, room temperature, 4 h 2: 95.2 percent / 30percent H2O2, 10percent aqueous NaOH / methanol / 0.25 h / 0 °C 3: 59 percent / p-TsNHNH2, AcOH / CH2Cl2 / 1.) - 20 deg C, 20 h, 2.) room temperature, 4 h 4: 78.7 percent / tetrahydrofuran; diethyl ether / 1 h / 0 °C 5: 63.9 percent / LiNH2, NH3 / tetrahydrofuran / 5 h / -33 °C 6: 1.) (CF3CO)2O, 2.) KOH / 1.) CF3CO2H, - 18 deg C, 2 h, 2.) EtOH, room temperature, 4 h View Scheme
参考文献
Kametani, Tetsuji; Suzuki, Koji; Nemoto, Hideo
Tetrahedron Letters, 1980 , vol. 21, p. 1469 - 1470
