N-亚苄基-4-甲基苯磺酰胺合成路线 （共 129 条）
反应条件
1.1: LDA / tetrahydrofuran / 1 h / -78 °C
1.2: 100 percent / tetrahydrofuran / 2 h / -78 °C
2.1: 100 percent / LAH / tetrahydrofuran / 1 h / 0 - 20 °C
3.1: TsCl; KOH / tetrahydrofuran / 0.5 h / Heating
View Scheme
参考文献
Ghorai, Manas K.; Das, Kalpataru; Kumar, Amit; Das, Animesh
Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5393 - 5397
反应条件
in toluene
T=120°C; 12 h; Inert atmosphere; optical yield given as percent de;
参考文献
Yan, Yizhe; Xu, Kun; Fang, Yang; Wang, Zhiyong
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6849 - 6855
反应条件
copper dichloride in toluene
T=120°C; 12 h; Inert atmosphere; optical yield given as percent de;
参考文献
Yan, Yizhe; Xu, Kun; Fang, Yang; Wang, Zhiyong
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6849 - 6855
反应条件
1: 1,10-phenanthroline; palladium diacetate / tetrahydrofuran / 24 h / 120 °C / Inert atmosphere
2: toluene / 120 °C
View Scheme
参考文献
Yan, Yizhe; Xu, Kun; Fang, Yang; Wang, Zhiyong
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6849 - 6855
反应条件
FeCl3·6H2O in dichloromethane
T=0 - 20°C; Friedel Crafts arylation; 2.5 h; Inert atmosphere;
参考文献
Thirupathi, Ponnaboina; Soo Kim, Sung
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5240 - 5249
反应条件
chloro-trimethyl-silane; bismuth sulphate in dichloromethane
T=20°C; Friedel-Crafts reaction; 0.3 h;
参考文献
Liu, Cong-Rong; Li, Man-Bo; Yang, Cui-Feng; Tian, Shi-Kai
Chemical Communications, 2008 , # 10 p. 1249 - 1251
反应条件
1: 59 percent / air; Me2Zn / hexane / 49 h / 20 °C
2: 94 percent / TFA / 1 h / 0 °C
View Scheme
参考文献
Yamada, Ken-Ichi; Yamamoto, Yasutomo; Maekawa, Masaru; Tomioka, Kiyoshi
Journal of Organic Chemistry, 2004 , vol. 69, # 5 p. 1531 - 1534
反应条件
chloro-trimethyl-silane; bismuth sulphate in dichloromethane
T=20°C; Friedel-Crafts reaction; 1 h;
参考文献
Liu, Cong-Rong; Li, Man-Bo; Yang, Cui-Feng; Tian, Shi-Kai
Chemical Communications, 2008 , # 10 p. 1249 - 1251
反应条件
dimethyl sulfoxide
T=20°C; Knoevenagel condensation; 24 h; Inert atmosphereMolecular sieve; optical yield given as percent destereoselective reaction;
参考文献
Chiba, Ryoichi; Oriyama, Takeshi
Chemistry Letters, 2008 , vol. 37, # 12 p. 1218 - 1219
