奎宁环-3-甲腈合成路线

参考文献

Orlek, Barry S.; Blaney, Frank E.; Brown, Frank; Clark, Michael S. G.; Hadley, Michael S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2726 - 2735

51627-76-0奎宁环-3-甲腈

75208-40-1奎宁环-3-羧酸

参考文献

Orlek, Barry S.; Blaney, Frank E.; Brown, Frank; Clark, Michael S. G.; Hadley, Michael S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2726 - 2735

51627-76-0奎宁环-3-甲腈

174407-35-3

参考文献

MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2006/69097 A2, 2006 ;
Location in patent: Page/Page column 47 ;
WO 2006/069097 A2

51627-76-0奎宁环-3-甲腈

6238-34-2奎宁环-3-甲酸盐酸盐

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; EVERITT, Simon; KNEGTEL, Ronald; MORTIMORE, Michael; RUTHERFORD, Alistair
Patent: WO2013/43960 A1, 2013 ;
Location in patent: Paragraph 00159 ;

51627-76-0奎宁环-3-甲腈

38206-86-9

参考文献

Orlek, Barry S.; Blaney, Frank E.; Brown, Frank; Clark, Michael S. G.; Hadley, Michael S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2726 - 2735

3731-38-23-奎宁环酮+

38622-91-2

51627-76-0奎宁环-3-甲腈

参考文献

BAYER HEALTHCARE AG
Patent: WO2005/12299 A1, 2005 ;
Location in patent: Page/Page column 18 ;

3731-38-23-奎宁环酮

51627-76-0奎宁环-3-甲腈

参考文献

MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2006/69097 A2, 2006 ;
Location in patent: Page/Page column 46-47 ;
WO 2006/069097 A2

38622-91-2+

1193-65-33-奎宁环酮盐酸盐

51627-76-0奎宁环-3-甲腈

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; MORTIMORE, Michael; EVERITT, Simon; RUTHERFORD, Alistair; KNEGTEL, Ronald
Patent: WO2013/43961 A1, 2013 ;
Location in patent: Paragraph 00156 ;
WO 2013/043961 A1

74384-65-9+

39085-59-12,4,6-三异丙基苯磺酰肼

51627-76-0奎宁环-3-甲腈

参考文献

Merck, Sharp and Dohme, Ltd.
Patent: US5686463 A1, 1997 ;

3731-38-23-奎宁环酮+

151-50-8氰化钾

51627-76-0奎宁环-3-甲腈

参考文献

Saunders, John; Cassidy, Mark; Freedman, Stephen B.; Harley, Elizabeth A.; Iversen, Leslie L.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1128 - 1138