1-甲基-4,4A,5,6,7,8-六氢-3H-萘-2-酮合成路线 （共 19 条）
反应条件
1: HCl / methanol / Heating
2: (i) NaH, benzene, (ii) /BRN= 969135/
3: aq. KOH / ethanol / Heating
View Scheme
参考文献
Banerjee,D.K. et al.
Tetrahedron, 1960 , vol. 8, p. 163 - 169
反应条件
(i) dioxane, (ii) NaOAc, aq. AcOH, (iii) (cyclization); Multistep reaction;
参考文献
Stork,G. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 207 - 222
反应条件
(i) Et2O, (ii) KOH, MeOH; Multistep reaction;
参考文献
Lansbury,P.T. et al.
Journal of the American Chemical Society, 1975 , vol. 97, p. 394 - 403
反应条件
(i), (ii) NaOMe, MeOH; Multistep reaction;
参考文献
Stork,G.; Ganem,B.
Journal of the American Chemical Society, 1973 , vol. 95, p. 6152 - 6153
参考文献
Dauben,W.G. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 11 p. 4060 - 4069
反应条件
ammonia; water; sodium
1.) methanol, THF, 2.) ethanol, reflux, 3h; Yield given. Multistep reaction;
参考文献
Stevens, Robert V.; Canary, Jimmy W.
Journal of Organic Chemistry, 1990 , vol. 55, # 7 p. 2237 - 2240
反应条件
1: 80 percent / 24 h / Ambient temperature
2: 1.) sodium, liquid ammonia, 2.) water / 1.) methanol, THF, 2.) ethanol, reflux, 3h
View Scheme
参考文献
Stevens, Robert V.; Canary, Jimmy W.
Journal of Organic Chemistry, 1990 , vol. 55, # 7 p. 2237 - 2240
反应条件
potassium hydroxide; ethanol; water
参考文献
Kawase
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 336
参考文献
Bhattacharyya
Journal of the Indian Chemical Society, 1956 , vol. 33, p. 545,551
