5-(4-氨基苯基)-1,3,4-噻二唑-2-胺合成路线 （共 6 条）
反应条件
hydrogen; nickel in ethanol
P=2206.5 Torr; 6 h;
参考文献
Chaudhan, P. M. S.; Pratap, Ram; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 1154 - 1157
反应条件
anhydrous iron chloride; sodium acetate in acetic acid
T=20°C; 0.5 h;
参考文献
Rajak, Harish; Agarawal, Avantika; Parmar, Poonam; Thakur, Bhupendra Singh; Veerasamy, Ravichandran; Sharma, Prabodh Chander; Kharya, Murli Dhar
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5735 - 5738
反应条件
1: phosphoric acid / 120 °C
2: 78 percent / H2 / Raney-Ni / ethanol / 6 h / 2206.5 Torr
View Scheme
参考文献
Chaudhan, P. M. S.; Pratap, Ram; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 1154 - 1157
反应条件
sulfuric acid
2 h; Reflux;
参考文献
Pattan; Kittur; Sastry; Jadav; Thakur; Madamwar; Shinde
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 4 p. 615 - 618
反应条件
1: sodium acetate / water / 20 °C
2: anhydrous iron chloride; sodium acetate / acetic acid / 0.5 h / 20 °C
View Scheme
参考文献
Rajak, Harish; Agarawal, Avantika; Parmar, Poonam; Thakur, Bhupendra Singh; Veerasamy, Ravichandran; Sharma, Prabodh Chander; Kharya, Murli Dhar
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5735 - 5738
反应条件
1: FeCl3+6H2O; H2O
2: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Eckenstein et al.
Helvetica Chimica Acta, 1950 , vol. 33, p. 1353,1360
