1: 4.2 g / tetrahydrofuran / 0.17 h / 0 °C 2: 99 percent / N,N,N',N'-tetramethylethylenediamine; s-BuLi / cyclohexane; tetrahydrofuran / -78 - 25 °C 3: 82 percent / HCl; acetic acid / H2O / 20 h / Heating View Scheme

1.1: dichloromethane / 12 h / 0 - 20 °C / |Inert atmosphere 2.1: sec.-butyllithium; N,N,N',N,-tetramethylethylenediamine / tetrahydrofuran; cyclohexane / 2 h / -78 °C / |Inert atmosphere 2.2: -78 - 20 °C / |Inert atmosphere 3.1: hydrogenchloride; acetic acid; water / 12 h / |Reflux View Scheme

暂无反应条件数据

1: triethylamine / CH2Cl2 / 4 h / Ambient temperature 2: sodium hydride / tetrahydrofuran / 18 h / Heating 3: 1.) potassiun, tert-butyl alcohol, ammonia / 1.) THF, -78 deg C, 2.) THF, -78 deg C, 1 h View Scheme

phosphorus pentachloride

thionyl chloride; N,N-dimethyl-formamide T=25°C;

1.1: K2S2O8; CuSO4*5H2O / acetonitrile; H2O 1.2: 60 percent / NH2SO3H; NaClO2 / tetrahydrofuran; H2O 2.1: SOCl2 / Heating View Scheme