乙二醛-1,1-二甲基乙缩醛合成路线 （共 23 条）
参考文献
Heydrich, Gunnar; Aust, Nicola Christiane; Putter, Hermann; Fischer, Andreas; Botzem, Jorg
Patent: US2003/69451 A1, 2003 ;
反应条件
potassium phosphate buffer; benzaldehyde lyase from Pseudomonas fluorescens; magnesium sulfate; 2,4,4'-trichloro-2'-hydroxydiphenyl ether in dimethyl sulfoxide T=20°C; pH=7.0; 96 h;
参考文献
Organic Letters, , vol. 5, # 12 p. 2047 - 2050
参考文献
Societe Francaise Hoechst
Patent: US5550250 A1, 1996 ;
反应条件
potassium carbonate in water; toluene 2 h; Reflux; optical yield given as percent de;
参考文献
Hong, Bor-Cherng; Chen, Po-Yuan; Kotame, Prakash; Lu, Pei-Ying; Lee, Gene-Hsiang; Liao, Ju-Hsiou
Chemical Communications, 2012 , vol. 48, # 63 p. 7790 - 7792
反应条件
potassium carbonate in cyclohexane Heating; Yield given. Yields of byproduct given;
参考文献
Stambouli, A.; Amouroux, R.; Chastrette, M.
Tetrahedron Letters, 1987 , vol. 28, # 44 p. 5301 - 5302
反应条件
hydrogenchloride 1.) benzene, 18 h, 23 deg C 2.) benzene, 0 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Corey, E. J.; Kang, Myung-chol; Desai, Manoj C.; Ghosh, Arun K.; Houpis, Ioannis N.
Journal of the American Chemical Society, 1988 , vol. 110, # 2 p. 649 - 651
反应条件
1: C7H6FN3*ClH With potassium phosphate; N-methanesulfonylhydrazine in acetonitrile
T=20°C; 0.5 h;
2: glyoxal 1,1-dimethyl acetal in water; acetonitrile
T=70°C; 2.33333 - 2.5 h; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2006/293304 A1, 2006 ;
Location in patent: Page/Page column 35 ;
反应条件
in water
T=100°C; P=5.00075 Torr; 2 h; Heating / reflux;
参考文献
CLARIANT (FRANCE)
Patent: WO2004/13081 A1, 2004 ;
Location in patent: Page 45 ;
反应条件
1: methyl 8-(diethylphosphono)-9-oxodec-5(Z)-enoate With sodium hydride in tetrahydrofuran
T=-5°C; 2 h;
2: glyoxal 1,1-dimethyl acetal in tetrahydrofuran
T=-78 - -25°C;
参考文献
Amarnath, Venkataraman; Amarnath, Kalyani; Masterson, Tina; Davies, Sean; Roberts II, Jackson
Synthetic Communications, 2005 , vol. 35, # 3 p. 397 - 408
反应条件
1: in ethanol; water
T=20°C; 96 h;
2: With hydrogen; 5 Pd(II)/C(eggshell) in ethanol; water
P=2250.23 Torr; 20 h;
参考文献
Alcaraz, Lilian; Bailey, Andrew; Kindon, Nicholas
Patent: US2011/53909 A1, 2011 ;
Location in patent: Page/Page column 79 ;
