alpha-溴-N-甲基-2-苯乙酰胺合成路线 （共 4 条）
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=60°C; 168 h; Product distribution / selectivity;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2005/118548 A1, 2005 ;
Location in patent: Page/Page column 29 ;
WO 2005/118548 A1
反应条件
1: 79 percent / Et3N
2: 89 percent / Et3N, LiBr / CH2Cl2
View Scheme
参考文献
Hoffman, Robert V.; Nayyar, Naresh K.; Klinekole, Bruce W.
Journal of the American Chemical Society, 1992 , vol. 114, # 15 p. 6262 - 6263
反应条件
triethylamine; lithium bromide in dichloromethane
参考文献
Hoffman, Robert V.; Nayyar, Naresh K.; Klinekole, Bruce W.
Journal of the American Chemical Society, 1992 , vol. 114, # 15 p. 6262 - 6263
参考文献
Truitt et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 3479
