1: 3-hydroxy-3-phenylpropyl 4-toluenesulfonate With 3 A molecular sieve; oxygen; (-)-sparteine; palladium diacetate in toluene T=80°C; P=760 Torr; 36 h; 2: methylamine With water in tetrahydrofuran T=65°C; 3: ortho-cresol With hydrogenchloride; triphenylphosphine; diethylazodicarboxylate in diethyl ether T=-10 - 0°C;

1: 3-hydroxy-3-phenylpropyl 4-toluenesulfonate With 3 A molecular sieve; oxygen; (-)-sparteine; palladium diacetate in toluene T=80°C; P=760 Torr; 36 h; 2: methylamine With water in tetrahydrofuran T=65°C;

1: 3-hydroxy-3-phenylpropyl 4-toluenesulfonate With 3 A molecular sieve; oxygen; (-)-sparteine; palladium diacetate in toluene T=80°C; P=760 Torr; 36 h; 2: methylamine With water in tetrahydrofuran T=65°C; 3: 1-chloro-4-(trifluoromethyl)benzene With hydrogenchloride; N,N-dimethyl acetamide; sodium hydride in diethyl ether T=90 - 105°C;