2,6-二甲基-1,6-庚二烯合成路线 （共 15 条）
反应条件
dilithium tetrachlorocuprate in tetrahydrofuran
1.) -78 deg C, 1 h, 2.) 0 deg C, 6 h, 3.) room temperature, 18 h;
参考文献
Berkowitz, William F.; Wu, Yanzhong
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1536 - 1539
反应条件
titanium tetrachloride; zinc in tetrahydrofuran
1) 4-5 deg C , 3d, 2) r.t., 10h;
参考文献
Irrgang,B.; Mayr,H.
Tetrahedron, 1991 , vol. 47, p. 219
反应条件
1: 75 percent / Ph3P, NBS / CH2Cl2 / 3 h / Ambient temperature
2: 87 percent / Li2CuCl4 / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) 0 deg C, 6 h, 3.) room temperature, 18 h
View Scheme
参考文献
Berkowitz, William F.; Wu, Yanzhong
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1536 - 1539
反应条件
dimethyl sulfoxide
T=180°C; 16 h; Yield given;
参考文献
Molnar, Arpad; Bartok, Mihaly
Helvetica Chimica Acta, 1981 , vol. 64, # 2 p. 389 - 398
反应条件
1: pyridine
2: NaI / acetone
3: (i) Mg, Et2O, (ii) /BRN= 385737/
4: (i) PhLi, Et2O, (ii) /BRN= 3599467/
View Scheme
参考文献
Ansell,M.F.; Thomas,D.A.
Journal of the Chemical Society, 1961 , p. 539 - 542
反应条件
1: NaI / acetone
2: (i) Mg, Et2O, (ii) /BRN= 385737/
3: (i) PhLi, Et2O, (ii) /BRN= 3599467/
View Scheme
参考文献
Ansell,M.F.; Thomas,D.A.
Journal of the Chemical Society, 1961 , p. 539 - 542
参考文献
Uijttewaal,A.P. et al.
Journal of Organic Chemistry, 1979 , vol. 44, p. 3157 - 3168
反应条件
oxalic acid
Heating;
参考文献
Casteignau,G.; Villessot,D.
Bulletin de la Societe Chimique de France, 1968 , p. 3893 - 3903
反应条件
1: DMSO / 18 h / 180 °C
2: DMSO / 16 h / 180 °C
View Scheme
参考文献
Molnar, Arpad; Bartok, Mihaly
Helvetica Chimica Acta, 1981 , vol. 64, # 2 p. 389 - 398
反应条件
titanium tetrachloride; zinc
1.) THF, 5 deg C, 3 d, 2.) THF, CH2Cl2, RT, 4 h; Yield given. Multistep reaction;
参考文献
Connor, Dennis A.; Arnold, Donald R.; Bakshi, Pradip K.; Cameron, T. Stanley
Canadian Journal of Chemistry, 1995 , vol. 73, # 6 p. 762 - 771
