外消旋赤式-3-氨基壬烷-2-醇合成路线 （共 4 条）
反应条件
hydrogen; palladium dihydroxide in methanol
P=760 Torr; 12 h; Ambient temperature; Yield given;
参考文献
Marco, Jose L.; Royer, Jacques; Husson, Henri-Philippe
Tetrahedron Letters, 1985 , vol. 26, # 51 p. 6345 - 6348
反应条件
1: 1) LDA / 1) THF, HMPT, -78 deg C, 2) 1 h
2: 2) 20percent HCl / 1) THF, ether, -78 deg C, 1 h, 2) r.t., 3 h
3: NaBH4 / methanol / 3 h / Ambient temperature
4: H2 / Pd(OH)2 / methanol / 12 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Marco, Jose L.; Royer, Jacques; Husson, Henri-Philippe
Tetrahedron Letters, 1985 , vol. 26, # 51 p. 6345 - 6348
反应条件
1: NaBH4 / methanol / 3 h / Ambient temperature
2: H2 / Pd(OH)2 / methanol / 12 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Marco, Jose L.; Royer, Jacques; Husson, Henri-Philippe
Tetrahedron Letters, 1985 , vol. 26, # 51 p. 6345 - 6348
反应条件
1: 2) 20percent HCl / 1) THF, ether, -78 deg C, 1 h, 2) r.t., 3 h
2: NaBH4 / methanol / 3 h / Ambient temperature
3: H2 / Pd(OH)2 / methanol / 12 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Marco, Jose L.; Royer, Jacques; Husson, Henri-Philippe
Tetrahedron Letters, 1985 , vol. 26, # 51 p. 6345 - 6348
