顺-二环[3.3.0]辛烷-3,7-二酮合成路线 （共 16 条）
反应条件
hydrogenchloride; acetic acid in water 3.5 h; RefluxInert atmosphere;
参考文献
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD.
Patent: US2012/184543 A1, 2012 ;
Location in patent: Page/Page column 46 ;
反应条件
hydrogenchloride in acetone T=20°C;
参考文献
Harrowven, David C; Lucas, Matthew C; Howes, Peter D
Tetrahedron, 2001 , vol. 57, # 44 p. 9157 - 9162
反应条件
hydrogenchloride in water 3 h; Heating;
参考文献
Bertz, Steven H.; Rihs, G.; Woodward, R.B.
Tetrahedron, 1982 , vol. 38, # 1 p. 63 - 70
反应条件
hydrogenchloride; acetic acid 1 h; Heating;
参考文献
Lannoye, G.; Sambasivarao, Kotha; Wehrli, S.; Cook, J. M.; Weiss, U.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2327 - 2340
反应条件
1: 81.8 percent / diethyl ether / -58 - 20 °C View Scheme
参考文献
Lannoye, G.; Sambasivarao, Kotha; Wehrli, S.; Cook, J. M.; Weiss, U.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2327 - 2340
反应条件
1: 80 percent / Sodium Amalgam / diethyl ether; H2O View Scheme
参考文献
Docken, Adrian M.
Journal of Organic Chemistry, 1981 , vol. 46, # 20 p. 4096 - 4097
反应条件
1: Sodium Amalgam View Scheme
参考文献
Docken, Adrian M.
Journal of Organic Chemistry, 1981 , vol. 46, # 20 p. 4096 - 4097
反应条件
2: aq. HCl View Scheme
参考文献
Osterthun,V.; Winterfeldt,E.
Chemische Berichte, 1977 , vol. 110, p. 146 - 153
反应条件
Yield given. Multistep reaction;
参考文献
Lannoye, G.; Sambasivarao, Kotha; Wehrli, S.; Cook, J. M.; Weiss, U.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2327 - 2340
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Lannoye, G.; Sambasivarao, Kotha; Wehrli, S.; Cook, J. M.; Weiss, U.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2327 - 2340
