4-羟基-2-氧代-2H-色烯-3-甲醛合成路线 （共 15 条）
反应条件
trichlorophosphate T=25 - 50°C; Vilsmayer-type reaction; 12.25 h; Heating / reflux;
参考文献
CLARIANT INTERNATIONAL LTD.
Patent: EP1516895 A1, 2005 ;
Location in patent: Page/Page column 6 ;
反应条件
1: With sodium hydroxide in water T=20°C; 2: With acetic acid in water
参考文献
Ibrahim, Magdy A.
Tetrahedron, 2009 , vol. 65, # 36 p. 7687 - 7690
反应条件
1: With sodium hydroxide in water T=20°C; 2: With acetic acid in water
参考文献
Ibrahim, Magdy A.
Tetrahedron, 2009 , vol. 65, # 36 p. 7687 - 7690
反应条件
water; toluene-4-sulfonic acid Heating;
参考文献
Rahman; Khan; Siddiqi; Zaman
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 10 p. 941 - 943
反应条件
1: p-TsOH*H2O / 0.03 h / microwave irradiation 2: Na2CO3 / 20 °C / pH 4 View Scheme
参考文献
Milevskii; Chibisova; Solov'Eva; Anisimova; Lebedev; Ivanov; Traven
Chemistry of Heterocyclic Compounds, 2013 , vol. 48, # 12 p. 1781 - 1792
Khim. Geterotsikl. Soedin., 2013 , vol. 48, # 12 p. 1903 - 1915,13
反应条件
1,4-dioxane; N-methyl-N-formyl-aniline; trichlorophosphate anschliessend Behandeln mit Wasser;
参考文献
Ziegler; Maier
Monatshefte fuer Chemie, 1958 , vol. 89, p. 787
反应条件
methanol; sodium hydroxide; sulfuric acid 1) 1-3h, reflux, 2) 20 deg C, 15 - 30 min; Yield given. Multistep reaction;
参考文献
Shkumat, A. P.; Babich, Yu. P.; Pivnenko, N. S.; Kazarov, A. E.; Polyakov, V. K.; et al.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 11 p. 2618 - 2625,2340 - 2346
反应条件
water; sodium hydrogencarbonate Heating;
参考文献
Milevskii; Chibisova; Solov'Eva; Anisimova; Lebedev; Ivanov; Traven
Chemistry of Heterocyclic Compounds, 2013 , vol. 48, # 12 p. 1781 - 1792
Khim. Geterotsikl. Soedin., 2013 , vol. 48, # 12 p. 1903 - 1915,13
反应条件
1: N,N-dimethyl-formamide 2: dimethyl sulfoxide / 20 °C View Scheme
参考文献
Milevsky; Solov'Eva; Chibisova; Yarovenko; Zayakin; Chernyshev; Krayushkin; Traven
Russian Chemical Bulletin, 2012 , vol. 61, # 12 p. 2311 - 2321
Izv. Akad. Nauk, Ser. Khim., 2012 , # 12 p. 2290 - 2300,11
反应条件
1: N,N-dimethyl-formamide 2: dimethyl sulfoxide / 20 °C View Scheme
参考文献
Milevsky; Solov'Eva; Chibisova; Yarovenko; Zayakin; Chernyshev; Krayushkin; Traven
Russian Chemical Bulletin, 2012 , vol. 61, # 12 p. 2311 - 2321
Izv. Akad. Nauk, Ser. Khim., 2012 , # 12 p. 2290 - 2300,11
