1: (1-phenylpropyl)phosphonic acid di-o-tolyl ester With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: 4-[2-(dimethylamino)ethoxy]benzophenone in tetrahydrofuran; hexane T=-78°C; Horner reaction; 48 h;

1: 1.) 95percent potassium t-butoxide, n-butyllithium, TMEDA / 1.) hexane, r.t., 30 min; 2.) Et2O, -70 deg C to r.t., 3 h 2: 32percent H2SO4 / 16 h / 50 °C View Scheme

1: (1-phenylpropyl)phosphonic acid di-o-tolyl ester With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: 4-[2-(dimethylamino)ethoxy]benzophenone in tetrahydrofuran; hexane T=-78°C; Horner reaction; 48 h;

(i) NaH, 1,2-dimethoxy-ethane, (ii) /BRN= 1975250/; Multistep reaction;