3H-2-氧杂-1H-非那烯-1-酮合成路线 （共 20 条）
反应条件
1: 72 percent / H2 / 5percent Pd/C / acetic acid / 24 h / 60 °C / 2844.3 - 3102.9 Torr 2: 98 percent / diethyl ether 3: HCl / diethyl ether / 15 h / Ambient temperature 4: 10percent Pd/C / 12 h / 280 - 290 °C View Scheme
参考文献
Pourahmady, Naser; Vickery, Euin H.; Eisenbraun, Edmund J.
Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2590 - 2593
反应条件
1: 72 percent / H2 / 5percent Pd/C / acetic acid / 24 h / 60 °C / 2844.3 - 3102.9 Torr 2: 98 percent / diethyl ether 3: HCl / diethyl ether / 15 h / Ambient temperature 4: 58 percent / 10percent Pd/C / 12 h / 280 - 290 °C 5: 30 percent / LAH/AlCl3 View Scheme
参考文献
Pourahmady, Naser; Vickery, Euin H.; Eisenbraun, Edmund J.
Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2590 - 2593
反应条件
hydrogenchloride; palladium 10 on activated carbon; hydrogen in water; N,N-dimethyl-formamide 15 h; chemoselective reaction;
参考文献
Tetrahedron Letters, , vol. 51, # 39 p. 5200 - 5202
反应条件
T=250°C; P=250073 Torr;
参考文献
Cason; Wordie
Journal of Organic Chemistry, 1950 , vol. 15, p. 608,614, 615
反应条件
1: 72 percent / H2 / 5percent Pd/C / acetic acid / 24 h / 60 °C / 2844.3 - 3102.9 Torr
2: 98 percent / diethyl ether
3: HCl / diethyl ether / 15 h / Ambient temperature
4: diethyl ether / 1.) ether, room temp., 6 h, 2.) reflux, 1 h
5: 1.) anhydrous CuSO4, 2.) H2 / 2.) 5percent Pd/C / 1.) 120 deg C, 1 h, 2.) acetic acid, 50 deg C, 40 psi
View Scheme
参考文献
Pourahmady, Naser; Vickery, Euin H.; Eisenbraun, Edmund J.
Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2590 - 2593
反应条件
1: 72 percent / H2 / 5percent Pd/C / acetic acid / 24 h / 60 °C / 2844.3 - 3102.9 Torr
2: 98 percent / diethyl ether
3: HCl / diethyl ether / 15 h / Ambient temperature
4: 58 percent / 10percent Pd/C / 12 h / 280 - 290 °C
5: LAH/AlCl3
View Scheme
参考文献
Pourahmady, Naser; Vickery, Euin H.; Eisenbraun, Edmund J.
Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2590 - 2593
反应条件
dihydridotetrakis(triphenylphosphine)ruthenium(II); acetone in toluene
T=180°C; 6 h;
参考文献
Murahashi, Shun-Ichi; Naota, Takeshi; Ito, Keiichiro; Maeda, Yoshihiro; Taki, Hiroshi
Journal of Organic Chemistry, 1987 , vol. 52, # 19 p. 4319 - 4327
反应条件
dipotassium hydrogenphosphate; palladium diacetate
T=140°C; 36 h;
参考文献
Zhang, Yang-Hui; Shi, Bing-Feng; Yu, Jin-Quan
Angewandte Chemie, International Edition, 2009 , vol. 48, # 33 p. 6097 - 6100
Angewandte Chemie, 2009 , vol. 121, # 33 p. 6213 - 6216
反应条件
sodium tetrahydroborate in tetrahydrofuran
T=20°C; Reduction; 24 h;
参考文献
Clayden, Jonathan; Frampton, Christopher S.; McCarthy, Catherine; Westlund, Neil
Tetrahedron, 1999 , vol. 55, # 49 p. 14161 - 14184
反应条件
ammonium cerium(IV) nitrate; oxygen in water
T=20°C; 0.0833333 h;
参考文献
Adam, Waldemar; Casado, Alicia; Miranda, Miguel A.
Angewandte Chemie, 1987 , vol. 99, # 8 p. 818 - 819
