N-(4-甲酰基-2-硝基苯基)乙酰胺合成路线 （共 14 条）
参考文献
Cohn; Springer
Monatshefte fuer Chemie, 1903 , vol. 24, p. 91
反应条件
1: 75 percent / HCl / 2 h / 75 °C 2: 68 percent / NH2OH*HCl; NaOH / ethanol; H2O / 7 h / 20 °C 3: NaOH; diethyl chlorophosphate / dimethylsulfoxide-d6; D2O View Scheme
参考文献
Wallace, Karl J.; Morey, Jeroni; Lynch, Vincent M.; Anslyn, Eric V.
New Journal of Chemistry, 2005 , vol. 29, # 11 p. 1469 - 1474
反应条件
potassium permanganate
参考文献
Cohn; Springer
Monatshefte fuer Chemie, 1903 , vol. 24, p. 91
反应条件
1: 80 percent / NaBH4 / methanol / 0.5 h / Ambient temperature
2: 81 percent / 10percent aq. NaOH / methanol / 0.5 h / Ambient temperature
View Scheme
参考文献
Akhtar, M. Shamim; Seth, M.; Bhaduri, A. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 395 - 399
反应条件
nitric acid in water
T=0°C; 2 h;
参考文献
ABBOTT LABORATORIES
Patent: WO2004/76424 A1, 2004 ;
Location in patent: Page 326-327 ;
WO 2004/076424 A1
反应条件
pyridine; Dess-Martin periodane in dichloromethane
参考文献
Safonov, Igor G.; Heerding, Dirk A.; Keenan, Richard M.; Price, Alan T.; Erickson-Miller, Connie L.; Hopson, Christopher B.; Levin, Jenna L.; Lord, Kenneth A.; Tapley, Peter M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1212 - 1216
反应条件
1: 57 percent / BH3*THF / tetrahydrofuran / 0 - 20 °C
2: 83 percent / pyridine; Dess-Martin periodinane / CH2Cl2
View Scheme
参考文献
Safonov, Igor G.; Heerding, Dirk A.; Keenan, Richard M.; Price, Alan T.; Erickson-Miller, Connie L.; Hopson, Christopher B.; Levin, Jenna L.; Lord, Kenneth A.; Tapley, Peter M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1212 - 1216
反应条件
hydrogenchloride
T=40°C;
参考文献
Hodgson; Beard
Journal of the Chemical Society, 1927 , p. 25
反应条件
sodium acetate
man nitriert das Acetylierungsprodukt in konz. Schwefelsaeure oder in Eisessig mit Salpeterschwefelsaeure bei 0grad;
参考文献
Cohn; Springer
Monatshefte fuer Chemie, 1903 , vol. 24, p. 91
参考文献
Cohn; Springer
Monatshefte fuer Chemie, 1903 , vol. 24, p. 91
