N-(2-苯基乙基)环己胺合成路线 （共 19 条）
反应条件
methanesulfonic acid; 5 palladium on charcoal; hydrogen in hexane
T=60°C; chemoselective reaction;
参考文献
Rubio-Marques, Paula; Leyva-Perez, Antonio; Corma, Avelino
Chemical Communications, 2013 , vol. 49, # 74 p. 8160 - 8162
反应条件
1: benzene / 4 h / Heating
2: 63 percent / tetrahydrofuran / 1) 1h, 0 deg C, 2) 25 deg C, 6h
3: 93 percent / CuSO4*5H2O / methanol; H2O / 1.5 h / Heating
View Scheme
参考文献
Katritzky, Alan R.; Latif, Muhammad; Urogdi, Laszlo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 667 - 672
反应条件
1: 63 percent / tetrahydrofuran / 1) 1h, 0 deg C, 2) 25 deg C, 6h
2: 93 percent / CuSO4*5H2O / methanol; H2O / 1.5 h / Heating
View Scheme
参考文献
Katritzky, Alan R.; Latif, Muhammad; Urogdi, Laszlo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 667 - 672
反应条件
sodium hydrogencarbonate in dichloromethane
0.166667 h; Inert atmosphere;
参考文献
Wiese, Stefan; Badiei, Yosra M.; Gephart, Raymond T.; Mossin, Susanne; Varonka, Matthew S.; Melzer, Marie M.; Meyer, Karsten; Cundari, Thomas R.; Warren, Timothy H.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8850 - 8855
反应条件
di-tert-butyl peroxide
T=90°C; 72 h; Inert atmosphereNeat (no solvent);
参考文献
Wiese, Stefan; Badiei, Yosra M.; Gephart, Raymond T.; Mossin, Susanne; Varonka, Matthew S.; Melzer, Marie M.; Meyer, Karsten; Cundari, Thomas R.; Warren, Timothy H.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8850 - 8855
参考文献
Wegler; Pieper
Chemische Berichte, 1950 , vol. 83, p. 6,10
参考文献
Wieland; Schoepf; Hermsen
Justus Liebigs Annalen der Chemie, 1925 , vol. 444, p. 55
参考文献
Wieland; Schoepf; Hermsen
Justus Liebigs Annalen der Chemie, 1925 , vol. 444, p. 55
反应条件
T=120 - 130°C; P=15200 Torr; Hydrogenation;
参考文献
v.Braun; Blessing; Zobel
Chemische Berichte, 1923 , vol. 56, p. 1990
Chemische Berichte, 1923 , vol. 56, p. 1999
