2''-O-甲基异甘草苷元; 4,4'-二羟基-2'-甲氧基查耳酮合成路线 （共 11 条）
反应条件
sodium hydroxide in ethanol
T=20°C; 96 h;
参考文献
Lee, Eunyoung; Jang, Inhye; Shin, Min Jung; Cho, Hee-Ju; Kim, Jungsook; Eom, Ji-Eun; Kwon, Youngjoo; Na, Younghwa
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 9 p. 3459 - 3464
反应条件
1: 100 percent / TiCl4 / CH2Cl2 / 0.5 h / 0 - 20 °C
2: 78 percent / DBU / benzene / 0.33 h / 80 °C
3: 94 percent / Et3N; PPh3; Pd(OAc)2 / acetonitrile / 4 h / 85 °C
4: 100 percent / MeONa / tetrahydrofuran; methanol / 1 h
5: 9 mg / EtSNa / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
1: 94 percent / Et3N; PPh3; Pd(OAc)2 / acetonitrile / 4 h / 85 °C
2: 100 percent / MeONa / tetrahydrofuran; methanol / 1 h
3: 9 mg / EtSNa / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
1: 94 percent / Et3N; PPh3; Pd(OAc)2 / acetonitrile / 4 h / 85 °C
2: 100 percent / MeONa / tetrahydrofuran; methanol / 1 h
3: 9 mg / EtSNa / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
1: 78 percent / DBU / benzene / 0.33 h / 80 °C
2: 94 percent / Et3N; PPh3; Pd(OAc)2 / acetonitrile / 4 h / 85 °C
3: 100 percent / MeONa / tetrahydrofuran; methanol / 1 h
4: 9 mg / EtSNa / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
1: 100 percent / MeONa / tetrahydrofuran; methanol / 1 h
2: 9 mg / EtSNa / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
1: 82 percent / K2CO3
2: 51 percent / conc. HCl / acetic acid / 2 h / 48 °C
View Scheme
参考文献
Carlson, Robert E.; Dolphin, David H.
Phytochemistry (Elsevier), 1982 , vol. 21, # 7 p. 1733 - 1736
反应条件
potassium hydroxide in ethanol
24 h; Ambient temperature;
参考文献
Achenbach, Hans; Stoecker, Markus; Constenla, Manuel A.
Phytochemistry (Elsevier), 1988 , vol. 27, # 6 p. 1835 - 1842
反应条件
ethyl mercaptan sodium salt in N,N-dimethyl-formamide
3 h; Heating; Further byproducts given;
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
反应条件
ethyl mercaptan sodium salt in N,N-dimethyl-formamide
3 h; Heating; Further byproducts given;
参考文献
Bianco, Armandodoriano; Cavarischia, Claudia; Farina, Angela; Guiso, Marcella; Marra, Carolina
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9107 - 9110
