N-(5-甲基吡啶-2-基)哌啶-4-胺合成路线 (共 2 条)
反应条件
1: With sodium tris(acetoxy)borohydride; acetic acid in tetrahydrofuran
T=20°C; 70 h;
2: With trifluoroacetic acid in tetrahydrofuran; dichloromethane
T=20°C; 18 h;
参考文献
Kawamura, Koji; Miyoshi, Keita; Kobayashi, Emi
Patent: US2012/142932 A1, 2012 ;
Location in patent: Page/Page column 5 ;
反应条件
hydrogen bromide; acetic acid
参考文献
Kyorin Pharmaceutical Co., Ltd.; Nisshin Pharma Inc.
Patent: EP1443046 A1, 2004 ;
Location in patent: Page 26 ;
EP 1443046 A1