三甲基((4-((4-(苯基乙炔)苯基)乙炔)苯基)乙炔)硅烷合成路线 （共 10 条）
反应条件
1: trimethyl[4-(4-(phenylethynyl)phenylethynyl)phenylethynyl]silane With potassium hydroxide in tetrahydrofuran; methanol
T=25°C;
2: 4-(TMS-ethynyl)iodobenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; Sonogashira coupling; 24 h;
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
反应条件
1: 1-(phenylethynyl)-4-[(trimethylsilyl)ethynyl]benzene With potassium hydroxide in tetrahydrofuran; methanol
T=25°C;
2: 4-(TMS-ethynyl)iodobenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: KOH / methanol; tetrahydrofuran / 25 °C
1.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
2.1: KOH / methanol; tetrahydrofuran / 25 °C
2.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
View Scheme
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: KOH / methanol; tetrahydrofuran / 25 °C
1.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
2.1: KOH / methanol; tetrahydrofuran / 25 °C
2.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
View Scheme
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: BF3*Et2O; t-BuONO / diethyl ether / 0.5 h / -20 - 5 °C
1.2: 13.2 g / NaI; I2 / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
反应条件
1.1: Pd(PPh3)2Cl2; CuI; triethylamine / 20 °C
2.1: BF3*Et2O; t-BuONO / diethyl ether / 0.5 h / -20 - 5 °C
2.2: 13.2 g / NaI; I2 / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
反应条件
1: 96 percent / K2CO3 / CH2Cl2; methanol
2: 44 percent / PdCl2(PPh3)2; CuI; i-Pr2NEt / tetrahydrofuran / 24 h / 20 °C
View Scheme
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
反应条件
1.1: Pd(PPh3)2Cl2; CuI; triethylamine / 20 °C
2.1: BF3*Et2O; t-BuONO / diethyl ether / 0.5 h / -20 - 5 °C
2.2: 13.2 g / NaI; I2 / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
