2-(4-甲氧基苯基)喹啉-4-碳酰肼合成路线 （共 3 条）
反应条件
sulfuric acid
Reflux;
参考文献
Duan, Zhenfeng; Li, Xin; Huang, Haoxi; Yuan, Wei; Zheng, Shao-Liang; Liu, Xianzhe; Zhang, Zhan; Choy, Edwin; Harmon, David; Mankin, Henry; Hornicek, Francis
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3113 - 3121
反应条件
1: potassium hydroxide / ethanol / 24 h / 80 °C
2: sulfuric acid / Reflux
View Scheme
参考文献
Duan, Zhenfeng; Li, Xin; Huang, Haoxi; Yuan, Wei; Zheng, Shao-Liang; Liu, Xianzhe; Zhang, Zhan; Choy, Edwin; Harmon, David; Mankin, Henry; Hornicek, Francis
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3113 - 3121
反应条件
1.1: potassium hydroxide / ethanol / 24 h / 80 °C
1.2: 0 °C / pH 1
2.1: sulfuric acid / |Reflux
View Scheme
参考文献
THE GENERAL HOSPITAL CORPORATION; DUAN, Zhenfeng; HORNICEK, Francis J.
Patent: WO2013/126664 A1, 2013 ;
