2-氨基-5-(4-硝基苯基)-1,3,4-噁二唑合成路线 (共 10 条)
反应条件
hydrogenchloride in ethanol
4 h; Heating;
参考文献
Khare, R. K.; Srivastava, M. K.; Singh, H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 9 p. 828 - 831
反应条件
benzoyl chloride
1.) acetone, refluxed, 30 min.; 2.) 15 min.; Yield given. Multistep reaction;
参考文献
Naik; Meher; Nayak
Journal of the Indian Chemical Society, 1983 , vol. 60, # 7 p. 674 - 678
反应条件
1: benzoyl chloride / 1.) acetone, refluxed, 30 min.; 2.) 15 min.
2: NaOAc / ethanol / 6 h / Heating
View Scheme
参考文献
Naik; Meher; Nayak
Journal of the Indian Chemical Society, 1983 , vol. 60, # 7 p. 674 - 678
反应条件
bromine; sodium acetate in acetic acid
0.25 h;
参考文献
Bansal, R. K.; Bhagchandani, G.
Journal of the Indian Chemical Society, 1982 , vol. 59, # 2 p. 277 - 279
反应条件
in methanol
T=50 - 60°C; 5 h; Inert atmosphere;
参考文献
Tasaganva; Tambe; Kariduraganavar
Journal of Molecular Structure, 2011 , vol. 1000, # 1-3 p. 10 - 23
反应条件
sulfuric acid
2 h; Heating;
参考文献
Pradhan, Banasova; Misro; Padhy, Arun Kumar
Journal of the Indian Chemical Society, 2002 , vol. 79, # 11 p. 898 - 900
反应条件
1: sodium acetate / water / 20 °C
2: bromine; sodium acetate / acetic acid / 0.5 h / 20 °C
View Scheme
参考文献
Rajak, Harish; Agarawal, Avantika; Parmar, Poonam; Thakur, Bhupendra Singh; Veerasamy, Ravichandran; Sharma, Prabodh Chander; Kharya, Murli Dhar
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5735 - 5738
反应条件
water; iodine; potassium iodide; sodium hydroxide in ethanol
T=70°C;
参考文献
Guda, Dinneswara Reddy; Cho, Hyeon Mo; Lee, Myong Euy
RSC Advances, 2013 , vol. 3, # 21 p. 7684 - 7687
反应条件
1: ethanol / 70 °C
2: sodium hydroxide; potassium iodide; iodine; water / ethanol / 70 °C
View Scheme
参考文献
Guda, Dinneswara Reddy; Cho, Hyeon Mo; Lee, Myong Euy
RSC Advances, 2013 , vol. 3, # 21 p. 7684 - 7687
反应条件
(i) N2H4*H2O, EtOH, (ii) /BRN= 3595135/, aq. HCl, (iii) Pb3O4, DMF; Multistep reaction;
参考文献
Yale; Losee
Journal of medicinal chemistry, 1966 , vol. 9, # 4 p. 478 - 483