1,4-二甲基-3,6-二氧代-2-哌嗪羧酸合成路线 （共 8 条）
参考文献
Chai, Christina L. L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron Letters, 2003 , vol. 44, # 2 p. 263 - 265
反应条件
1: TFA / CHCl3 / 16 h / 20 °C
2: 4.59 g / toluene / 24 h / Heating
3: 89 percent / K2CO3 / acetone / 48 h / Heating
4: H2 / Pd/C / methanol / 1 h
View Scheme
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
反应条件
1: H2 / Pd/C / methanol / 16 h
2: 1.99 g / toluene / 48 h / Heating
3: KOH / H2O; ethanol
View Scheme
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
反应条件
1: 79 percent / 16 h / 180 °C
2: H2 / Pd/C / methanol / 1 h
View Scheme
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
反应条件
1: 89 percent / K2CO3 / acetone / 48 h / Heating
2: H2 / Pd/C / methanol / 1 h
View Scheme
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
反应条件
hydrogen; palladium on activated charcoal in methanol
1 h; Title compound not separated from byproducts;
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
反应条件
hydrogen; palladium on activated charcoal
参考文献
Chai, Christina L. L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron Letters, 2003 , vol. 44, # 2 p. 263 - 265
反应条件
potassium hydroxide in ethanol; water
参考文献
Chai, Christina L.L.; Elix, John A.; Huleatt, Paul B.
Tetrahedron, 2005 , vol. 61, # 36 p. 8722 - 8739
