11-(四氢-2H-吡喃-2-基氧基)-1-十一碳炔合成路线 （共 6 条）
反应条件
1: n-BuLi; HMPA / tetrahydrofuran / -78 °C 2: PTS; MeOH / Heating 3: 100 percent / hydrogen / Pd/C / ethanol / 20 °C View Scheme
参考文献
Sharma, Anubha; Gamre, Sunita; Chattopadhyay, Subrata
Tetrahedron Letters, 2007 , vol. 48, # 21 p. 3705 - 3707
反应条件
1: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 2: 16percent H2SO4 / ethanol / 1 h / 50 °C 3: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 4: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 2: 16percent H2SO4 / ethanol / 1 h / 50 °C 3: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C View Scheme
参考文献
Cryle, Max J.; Hayes, Patricia Y.; De Voss, James J.
Chemistry - A European Journal, 2012 , vol. 18, # 50 p. 15994 - 15999
反应条件
1: CH3Li / tetrahydrofuran; hexamethylphosphoric acid triamide
2: P(C6H5)3*Br2 / CH2Cl2
3: CH3Li / tetrahydrofuran; hexamethylphosphoric acid triamide
4: acetic acid
5: hydrogen / P2-Ni
View Scheme
参考文献
Schwarz, Meyer; Klun, J. A.; Leonhardt, B. A.; Johnson, D. T.
Tetrahedron Letters, 1983 , vol. 24, # 10 p. 1007 - 1010
反应条件
1: 90 percent / 1.) Cp2Zr(Cl)h, 2.) I2 / benzene / 1.) 20-25 deg C, 7 h
2: 94 percent / PPTS / ethanol / 4 h / 55 °C
View Scheme
参考文献
Stille,J.K.; Simpson,J.H.
Journal of the American Chemical Society, 1987 , vol. 109, p. 2138
反应条件
1: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h
2: 16percent H2SO4 / ethanol / 1 h / 50 °C
View Scheme
参考文献
Cryle, Max J.; Hayes, Patricia Y.; De Voss, James J.
Chemistry - A European Journal, 2012 , vol. 18, # 50 p. 15994 - 15999
