2-氯乙氧基-2-乙氧基二乙醇合成路线 （共 57 条）
反应条件
1: 43 percent / triphenylphosphine; diethyl azodicarboxylate / toluene / 2 h / 20 °C
2: 55 percent / K2CO3; KI / acetonitrile / 48 h / Heating
View Scheme
参考文献
Gruen, Alajos; Koszegi, Eva; Bitter, Istvan
Tetrahedron, 2004 , vol. 60, # 23 p. 5041 - 5048
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=50°C;
参考文献
Mertens, Ingrid J. A.; Wegh, Rene; Jenneskens, Leonardus W.; Vlietstra, Edward J.; Van Der Kerk-van Hoof, Anca; Zwikker, Jan W.; Cleij, Thomas J.; Smeets, Wilberth J. J.; Veldman, Nora; Spek, Anthony L.
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 3 p. 725 - 736
反应条件
1: 72 percent / KOH / butan-1-ol; dimethylformamide / 20 h / Heating
2: pyridine / 0 - 5 °C
3: 78 percent / KOH / dimethylformamide; ethanol / 4 h / Heating
4: 95 percent / Raney nickel, 30percent aq. H4N2 solution / ethanol
View Scheme
参考文献
Sieger, Heinz; Voegtle, Fritz
Liebigs Annalen der Chemie, 1980 , # 3 p. 425 - 440
反应条件
in N,N-dimethyl-formamide
T=100°C; 18 h;
参考文献
Lu, Genliang; Lam, Sang; Burgess, Kevin
Chemical Communications, 2006 , # 15 p. 1652 - 1654
反应条件
1: 58.3 g / sodium iodide / butan-2-one / 19 h / Heating
2: 16.7 g / dimethylformamide / 18 h / 95 °C
View Scheme
参考文献
Slama, James; Rando, Robert R.
Carbohydrate Research, 1981 , vol. 88, p. 213 - 222
反应条件
1: 89 percent / DMF / 17 h / Heating
2: 90 percent / Jones reagent / acetone / 1 h
View Scheme
参考文献
Slama, James; Rando, Robert R.
Carbohydrate Research, 1981 , vol. 88, p. 213 - 222
反应条件
1: 70 percent / KOH / butan-1-ol / 16 h / Heating
2: 1.) NaH, 2.) conc. HCl / 1.) THF, 20 h, reflux, 2.) EtOH, 3 h, reflux
View Scheme
参考文献
Loehr, Hans-Gerd; Voegtle, Fritz
Chemische Berichte, 1985 , vol. 118, # 3 p. 914 - 921
参考文献
Gerhardt,W.; Kucharski,S.
Journal fuer Praktische Chemie (Leipzig), 1977 , vol. 319, p. 705 - 712
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
48 h; Heating;
参考文献
Gunning, Patrick; Benniston, Andrew C.; Peacock, Robert D.
Chemical Communications, 2004 , # 19 p. 2226 - 2227
参考文献
Czech, B.; Czech, A.; Bartsch, R. A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 341 - 343
