N-叔丁氧羰基-L-苯丙氨酸甲酯合成路线 （共 114 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
参考文献
LUCKY LTD.
Patent: EP601486 A1, 1994 ;
反应条件
sodium carbonate in water; ethyl acetate T=0 - 16°C;
参考文献
Sun, Dequn; Zhang, Lingzi; Wang, Jin
Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322
反应条件
lithium hydroxide in tetrahydrofuran Methylation; esterification; 1 h; Heating;
参考文献
Chakraborti, Asit K.; Basak, Anindita; Grover, Vikas
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8014 - 8017
反应条件
4 A molecular sieve in diethyl ether T=-40°C; 15 h; Title compound not separated from byproducts.;
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
potassium hydroxide; dipyridinium dichromate in methanol; N,N-dimethyl-formamide T=20°C;
参考文献
Morita; Nagasawa; Yahiro; Matsunaga; Kunieda
Organic letters, 2001 , vol. 3, # 6 p. 897 - 899
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran 0.25 h;
参考文献
Takeda; Akiyama; Nakamura; Takizawa; Mizuno; Takayanagi; Harigaya
Synthesis, 1994 , # 10 p. 1063 - 1066
反应条件
N,N,N',N,-tetramethylethylenediamine; PdCl2(Amphos)2; zinc in water T=20°C; Negishi coupling reaction; 16 h; Inert atmosphere;
参考文献
Ross, Andrew J.; Dreiocker, Frank; Schae Fer, Mathias; Oomens, Jos; Meijer, Anthony J.H.M.; Pickup, Barry T.; Jackson, Richard F.W.
Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1727 - 1734
反应条件
Yield given. Multistep reaction;
参考文献
You, Jingsong; Wroblewski, Andrzej E.; Verkade, John G.
Tetrahedron, 2004 , vol. 60, # 36 p. 7877 - 7883
反应条件
sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Ambient temperature;
参考文献
Beugelmans, Rene; Neuville, Luc; Bois-Choussy, Michele; Chastanet, Jacqueline; Zhu, Jieping
Tetrahedron Letters, 1995 , vol. 36, # 18 p. 3129 - 3132
反应条件
1: (S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-phenylmethyl-1-ethanol With Dess-Martin periodane in dichloromethane 2: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in water; tert-butyl alcohol 3: diazomethyl-trimethyl-silane in methanol; toluene
参考文献
Harvey, Joanne E.; Kenworthy, Martin N.; Taylor, Richard J. K.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2467 - 2471
