N-苯基邻苯二甲酰亚胺合成路线 （共 237 条）
反应条件
1: Et4NCl / acetonitrile / electrochemical reduction, Hg-cathode
2: 54 percent / acetonitrile / 20 °C
View Scheme
参考文献
Troll, T.; Ollmann, G. W.
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3497 - 3500
反应条件
1: 90 percent / NaBH4 / methanol; tetrahydrofuran / 2 h / 0 - 5 °C
2: toluene / 1 h / Heating
View Scheme
参考文献
Ishihara; Kiyota; Goto
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 11 p. 3024 - 3030
反应条件
1: 90 percent / NaBH4 / methanol; tetrahydrofuran / 2 h / 0 - 5 °C
2: toluene / 1 h / Heating
3: K2CO3 / methanol; H2O / 2 h / Heating
View Scheme
参考文献
Ishihara; Kiyota; Goto
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 11 p. 3024 - 3030
反应条件
chlorosulfonic acid
T=30 - 75°C; 2 h;
参考文献
Cremlyn, R. J.; Thandi, K.; Wilson, R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 1 p. 94 - 96
反应条件
1: chlorosulfuric acid
2: water; dioxane; ammonia
View Scheme
参考文献
Picard et al.
Journal of the Chemical Society, 1948 , p. 821
反应条件
1: 54 percent
2: 1.) SOCl2 2.) tetrabutylammonium azide / 1.) SOCl2, benzene, 48 h, RT 2.) tetrabutylammonium azide, acetonitrile, 1 h, RT
3: 53 percent / xylene / Heating
View Scheme
参考文献
Takeuchi, Hisato; Eguchi, Shoji
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2149 - 2154
反应条件
ethanol; ammonia; water
参考文献
Kuhara; Fukui
American Chemical Journal, 1901 , vol. 26, p. 457
参考文献
Laurent; Gerhardt
Annales de Chimie (Cachan, France), 1848 , vol. <3> 24, p. 191
Justus Liebigs Annalen der Chemie, 1848 , vol. 68, p. 36
反应条件
1: zinc chloride / 180 °C / Kochen des Produkts mit alkoh. Kali
View Scheme
参考文献
Doebner
Justus Liebigs Annalen der Chemie, 1881 , vol. 210, p. 267
反应条件
1: 5-bromo-1,2,3-trimethoxy-benzene With n-butyllithium in tetrahydrofuran
T=-78°C; 0.5 h; Inert atmosphere;
2: With zinc(II) chloride in tetrahydrofuran
T=-78 - 20°C; 0.5 h; Inert atmosphere;
3: N-phenyl phthalimide With [2,2']bipyridinyl; bis(1,5-cyclooctadiene)nickel (0) in tetrahydrofuran; 1,4-dioxane
T=95°C; 16 h; Inert atmosphere;
参考文献
Havlik, Sarah E.; Simmons, Jessica M.; Winton, Valerie J.; Johnson, Jeffrey B.
Journal of Organic Chemistry, 2011 , vol. 76, # 9 p. 3588 - 3593
