4-氯-3H-1-异苯并呋喃酮合成路线 （共 7 条）
参考文献
Nikulin, V. I.; Pisarenko, L. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1985 , vol. 34, # 1 p. 141 - 144
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985 , # 1 p. 151 - 155
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 0.5 h; 2: With hydrogenchloride; copper(l) chloride in water T=0 - 20°C; Sandmeyer reaction; Reflux;
参考文献
Wang, Wei; Cha, Xue-Xiang; Reiner, John; Gao, Yuan; Qiao, Hai-Ling; Shen, Jia-Xiang; Chang, Jun-Biao
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1941 - 1946
反应条件
lithium borohydride in tetrahydrofuran Yields of byproduct given;
参考文献
Soucy, C.; Favreau, D.; Kayser, M. M.
Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134
反应条件
oxygen in acetic acid; xylene T=35 - 40°C; Purification / work up;
参考文献
General Electric Company
Patent: US6670487 B1, 2003 ;
Location in patent: Page column 15 ;
反应条件
1: 40 percent / cetyltrimethylammonium bromide, KMnO4 / H2O / 24 h / 50 - 60 °C 2: 95 percent / acetic anhydride / 1 h / Heating 3: L-selectride / tetrahydrofuran / 24 h / 0 - 22 °C View Scheme
参考文献
Soucy, C.; Favreau, D.; Kayser, M. M.
Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134
反应条件
1: 95 percent / acetic anhydride / 1 h / Heating 2: L-selectride / tetrahydrofuran / 24 h / 0 - 22 °C View Scheme
参考文献
Soucy, C.; Favreau, D.; Kayser, M. M.
Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134
反应条件
lithium aluminium tetrahydride
参考文献
Tirouflet
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1954 , vol. 238, p. 2246
