(S)-(+)-2-己醇合成路线 （共 56 条）
反应条件
1: 91 percent / Na2CO3, Raney-nickel / ethanol / Heating 2: 89 percent / p-TsOH, CH3OH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Noe, Christian R.; Knollmueller, M.; Dungler, K.; Miculka, C.; Gaertner, P.
Monatshefte fuer Chemie, 1991 , vol. 122, # 8 p. 705 - 718
反应条件
1: 76 percent / Na2CO3, Raney-nickel / ethanol / Heating 2: 92 percent / p-TsOH, CH3OH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Noe, Christian R.; Knollmueller, M.; Dungler, K.; Miculka, C.; Gaertner, P.
Monatshefte fuer Chemie, 1991 , vol. 122, # 8 p. 705 - 718
反应条件
1: [Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; trifuran-2-yl-phosphane; sodium carbonate / toluene / 120 h / 65 °C 2: platinum(IV) oxide; hydrogen / isopropyl alcohol / 5 h / 20 °C 3: water; potassium hydroxide / ethanol / Reflux View Scheme
参考文献
Kalinowska, Iwona M.; Szawkao, Joanna; Krawczyk, Krzysztof K.; Maurin, Jan K.; Czarnocki, Zbigniew
Synthesis, 2011 , # 11 p. 1809 - 1813
反应条件
1: sec-alkylsulfatase Pisa1 / 72 h / 30 °C / pH 8.2 / aq. buffer; Enzymatic reaction 2: palladium 10 on activated carbon; hydrogen / 16 h / 760.05 Torr View Scheme
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
1: triethylamine/sulphur trioxide complex; sodium hydride / paraffin oil 2: sec-alkylsulfatase Pisa1 / 72 h / 30 °C / pH 8.2 / aq. buffer; Enzymatic reaction 3: palladium 10 on activated carbon; hydrogen / 16 h / 760.05 Torr View Scheme
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
1: platinum(IV) oxide; hydrogen / isopropyl alcohol / 5 h / 20 °C 2: water; potassium hydroxide / ethanol / Reflux View Scheme
参考文献
Kalinowska, Iwona M.; Szawkao, Joanna; Krawczyk, Krzysztof K.; Maurin, Jan K.; Czarnocki, Zbigniew
Synthesis, 2011 , # 11 p. 1809 - 1813
反应条件
1: sec-alkylsulfatase Pisa1 / 24 h / 30 °C / pH 8.2 / aq. buffer; Enzymatic reaction 2: toluene-4-sulfonic acid / 1,4-dioxane; tert-butyl methyl ether; water / 2 h / 40 °C View Scheme
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
1: toluene-4-sulfonic acid / 1,4-dioxane; tert-butyl methyl ether; water / 2 h / 40 °C 2: palladium 10 on activated carbon; hydrogen / 16 h / 760.05 Torr View Scheme
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
palladium 10 on activated carbon; hydrogen P=760.051 Torr; 16 h;
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
sodium hydroxide Hydrogenation;
参考文献
Levene; Haller
Journal of Biological Chemistry, 1928 , vol. 79, p. 486
Journal of Biological Chemistry, 1929 , vol. 83, p. 598
