2-氨基-5-氯苯甲酰胺合成路线 （共 20 条）
反应条件
ammonium hydroxide 4 h; Ambient temperature;
参考文献
Mohiuddin, Ghulam; Reddy, Padala Satyanarayana; Ahmed, Khalil; Ratnam, Chengalvala Venkata
Journal of Chemical Research, Miniprint, 1987 , # 7 p. 1839 - 1868
反应条件
aceton-washed saccharomyces cerevisiae in water; dimethyl sulfoxide T=32°C;
参考文献
Blackie, Josie A.; Turner, Nicholas J.; Wells, Andrew S.
Tetrahedron Letters, 1997 , vol. 38, # 17 p. 3043 - 3046
参考文献
American Home Products Corporation
Patent: US5187168 A1, 1993 ;
反应条件
ammonia T=0°C; 0.5 h;
参考文献
Mahajan; Mahalakshmi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 5 p. 1299 - 1300
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Gita, Haruhisa; Sobe, Yoshiaki; Akaku, Haruo; Ekine, Rena; Oto, Yuso; Isawa, Satoru; Hayashi, Hideya
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 549 - 551
反应条件
ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in water; N,N-dimethyl-formamide T=20°C;
参考文献
Mahajan; Mahalakshmi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 5 p. 1299 - 1300
反应条件
1.1: diphenylphosphoryl chloride; Et3N / CHCl3 1.2: NH3 2.1: H2 / 5 percent Pd/C / ethanol View Scheme
参考文献
Gita, Haruhisa; Sobe, Yoshiaki; Akaku, Haruo; Ekine, Rena; Oto, Yuso; Isawa, Satoru; Hayashi, Hideya
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 549 - 551
反应条件
1: 35 percent / sulfuryl chloride; hydrochloric acid / diethyl ether / 1.5 h / 60 - 70 °C 2: 37 percent / thionyl chloride / 0.5 h / Heating 3: 68 percent / liq. ammonia / 0.5 h / 0 °C View Scheme
参考文献
Mahajan; Mahalakshmi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 5 p. 1299 - 1300
反应条件
potassium hydroxide; ethanol Heating / reflux;
参考文献
PAINCEPTOR PHARMA CORPORATION
Patent: WO2007/71055 A1, 2007 ;
Location in patent: Page/Page column Sheet 10/15 ;
WO 2007/071055 A1
参考文献
Dorsch
Journal fuer Praktische Chemie (Leipzig), 1886 , vol. <2> 33, p. 36
