4-氯-2,3,5,6-四氟吡啶合成路线 （共 18 条）
反应条件
in sulfolane molar ratio C5F5N/CaCl2 = 1/6.7; heating in vacuum (5 Torr) until 100 ml solvent are distilled off; addition of ethyleneglycol and heating to 210 °C (72 h);;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
2,3,11,12-dicyclohexano-1,4,7,10,13,16-hexaoxacyclo-octadecane; calcium chloride in sulfolane 5 h; Heating;
参考文献
Vaganova; Kusov; Rodionov; Shundrina; Malykhin
Russian Chemical Bulletin, 2007 , vol. 56, # 11 p. 2239 - 2246
反应条件
1: neat (no solvent) 2: further solvent(s) View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
2: steel wool / neat (no solvent) 3: further solvent(s) View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
1: neat (no solvent) 2: further solvent(s) View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
Catalyst M-Chromium oxide T=520°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Weigert, F. J.
Journal of Fluorine Chemistry, 1991 , vol. 53, # 1 p. 33 - 42
反应条件
chlorine T=400 - 405°C; 0.316667 h;
参考文献
Platonov; Maksimov; Dvornikova; Nikul'shin
Russian Journal of Organic Chemistry, 2005 , vol. 41, # 11 p. 1647 - 1653
反应条件
in further solvent(s) At 90 °C (4 h) in presence of CsF in 2,5,8,11,14-pentaoxapentadecane as solvent.;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
in sulfolane bomb tube; first at 50-80 °C (17 h), then at 110-130 °C (135 h);;
参考文献
Musgrave, W. K. R.
Chemistry and Industry (London, United Kingdom), 1969 , p. 943 - 947
反应条件
in dichloromethane T=-78 - -50°C; 0.916667 h; Further byproducts. Title compound not separated from byproducts.;
参考文献
Abo-Amer, Anwar; Frohn, Hermann-Josef; Steinberg, Christoph; Westphal, Ulrich
Journal of Fluorine Chemistry, 2006 , vol. 127, # 10 SPEC. ISS. p. 1311 - 1323
