N-(3-二甲氨基丙基)甲基丙烯酰胺合成路线 (共 10 条)
反应条件
1: methacrylic acid methyl ester With (10H)-phenothiazine; 4-methoxy-phenol in xylene T=70°C; Heating / reflux; 2: With titanium(IV) isopropylate; di(n-butyl)tin oxide in xylene T=70 - 103°C; Heating / reflux; 3: 3-(dimethylamino)-n-propylamine in xylene T=103 - 150°C; 4 h; Heating / reflux; Product distribution / selectivity;
参考文献
Liu, Leo Zhaoqing
Patent: US2008/234515 A1, 2008 ;
Location in patent: Page/Page column 3; 4; 5 ;
反应条件
T=150°C; P=7500.75 Torr; Microwave irradiation;
参考文献
CLARIANT FINANCE (BVI) LIMITED
Patent: US2011/89020 A1, 2011 ;
Location in patent: Page/Page column 9-10 ;
反应条件
1: methacrylic acid methyl ester With (10H)-phenothiazine; 4-methoxy-phenol Heating / refluxNeat (no solvent); 2: With di(n-butyl)tin oxide T=70 - 101°C; Heating / refluxNeat (no solvent); 3: 2-(dimethylamino)-ethanol; 3-(dimethylamino)-n-propylamine With titanium(IV) isopropylate Product distribution / selectivity; more than 3 stages;
参考文献
Liu, Leo Zhaoqing
Patent: US2008/234515 A1, 2008 ;
Location in patent: Page/Page column 4- 5 ;
反应条件
(10H)-phenothiazine in toluene T=175 - 185°C; 0.0333333 h; Microwave irradiation;
参考文献
Krull, Matthias; Kayser, Christoph; Morschhaeuser, Roman; Ritter, Helmut; Schmitz, Sarah
Patent: US2010/32284 A1, 2010 ;
Location in patent: Page/Page column 8 ;
参考文献
Chemische Fabrik Stockhausen and Cie.
Patent: US4237067 A1, 1980 ;
反应条件
tri-ruthenium(0)dodecacarbonyl in 1,4-dioxane T=100°C; P=9880 Torr; 18 h;
参考文献
Zhou, Da-Yang; Yoneda, Eiji; Onitsuka, Kiyotaka; Takahashi, Shigetoshi
Chemical Communications, 2002 , # 23 p. 2868 - 2869
参考文献
Texaco Development Corporation
Patent: US4256665 A1, 1981 ;
参考文献
American Cyanamid Company
Patent: US4267372 A1, 1981 ;
反应条件
T=200°C; also with methyl acrylate; var. temp. and reaction time; also in the presence of amidation catalysts; Product distribution;
参考文献
Shirshin, K.V.; Kazantsev, O.A.; Zil'berman, E.N.; Danov, S.M.; Salov, V.N.
J. Appl. Chem. USSR (Engl. Transl.), 1992 , vol. 65, # 6.2 p. 1379 - 1383,1148 - 1152
反应条件
in diethyl ether T=20°C; 24 h;
参考文献
Kitano, Hiromi; Imai, Makoto; Sudo, Kurao; Ide, Makoto
Journal of Physical Chemistry B, 2002 , vol. 106, # 43 p. 11391 - 11396