4-苯甲氧基-2-羟基苯甲醛合成路线 （共 31 条）
反应条件
potassium carbonate in acetone Heating;
参考文献
Dewick, Paul M.
Synthetic Communications, 1981 , vol. 11, # 10 p. 853 - 858
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide Heating;
参考文献
Thomas, Michael G.; Lawson, Chris; Allanson, Nigel M.; Leslie, Bruce W.; Bottomley, Joanna R.; McBride, Andrew; Olusanya, Oyinkan A.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 423 - 426
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; Methylation; 4 h;
参考文献
CONNEXIOS LIFE SCIENCES PVT. LTD.; RANGANATH RAO, Jagannath Madanahalli; ARUMUGAM, Nagarajan; ANSARI, Mohd Mudabbir; GUDLA, Chandrasekhar; PACHIYAPPAN, Shanmugam; RAMALINGAM, Manivannan; GEORGE, Jenson; ARUL, George Fernanda; BOMMEGOWDA, Y, Kenchegowda; ANGUPILLAI, Sathesh Kumar; KOTTAMALAI, Ramamoorthy; JIDUGU, Pradeep; RAO, D, Shivanageshwara
Patent: WO2012/11125 A1, 2012 ;
Location in patent: Page/Page column 145-146 ;
WO 2012/011125 A1
反应条件
potassium carbonate in acetone T=20°C;
参考文献
Huo, Xing; Ren, Xingfeng; Xu, Yanfen; Li, Xinyun; She, Xuegong; Pan, Xinfu
Tetrahedron Asymmetry, 2008 , vol. 19, # 3 p. 343 - 347
反应条件
1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 20 °C / Large scale reaction 2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 1.5 h / -30 °C 2.2: 2 h / -30 °C 3.1: N,N-diethylaniline / 3 h / 215 °C / Inert atmosphere 4.1: AlCl3, aluminium chloride; N,N-diethylaniline / dichloromethane / -10 - 0 °C 5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C 5.2: 16 h / 20 °C 6.1: toluene-4-sulfonic acid / 2 h / 20 °C / Large scale reaction View Scheme
参考文献
Tong, Ling; Xiong, Ruisheng; Jiang, Hong; Jiang, Xiangrui; Sun, Hongbin; Jiang, Hualiang; Shen, Jingshan
Heterocycles, 2010 , vol. 81, # 7 p. 1697 - 1702
反应条件
hydroxylamine-o-sulphonic acid in water; acetonitrile T=80°C;
参考文献
Johnson, Patrick S.; Underwood, Toby J.; Wheeler, Simon
Tetrahedron Letters, 2011 , vol. 52, # 25 p. 3226 - 3227
反应条件
1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 20 °C / Large scale reaction 2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 1.5 h / -30 °C 2.2: 2 h / -30 °C 3.1: N,N-diethylaniline / 3 h / 215 °C / Inert atmosphere 4.1: AlCl3, aluminium chloride; N,N-diethylaniline / dichloromethane / -10 - 0 °C View Scheme
参考文献
Tong, Ling; Xiong, Ruisheng; Jiang, Hong; Jiang, Xiangrui; Sun, Hongbin; Jiang, Hualiang; Shen, Jingshan
Heterocycles, 2010 , vol. 81, # 7 p. 1697 - 1702
反应条件
1: ethanol; sodium ethylate / anschliessend Erwaermen mit wss. Kalilauge 3: hydrogen chloride; acetic acid 4: hydrogen chloride View Scheme
参考文献
Davies et al.
Journal of the Chemical Society, 1950 , p. 3206,3212
反应条件
1: K2CO3; acetone 2: sodium ethylate; ethanol 3: sodium acetate / Erhitzen des Reaktionsprodukts unter vermindertem Druck 4: palladium/charcoal; acetic acid / Hydrogenation View Scheme
参考文献
Foster et al.
Journal of the Chemical Society, 1948 , p. 2254,2258
