1: conc. HCl / dioxane / 2 h / 50 - 60 °C 2: SeO2 / xylene / 6 h / Heating 3: N-bromosuccinimide, benzoylperoxide / CCl4 / 1 h / Heating View Scheme

dipyridinium dichromate in N,N-dimethyl-formamide 4 h; Ambient temperature;

sodium dichromate; sulfuric acid; acetic acid

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '10505958', constants.ctx, '0')">1-butyl-2-isopropyl-3-methylimidazolium triflimide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=20&deg;C;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78 - 20&deg;C;&nbsp;Methylation;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4948473', constants.ctx, '0')">magnesium</a> <br />&nbsp;ether, 1.) 1h, reflux, r.t.;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br /> &nbsp;