3,5-二甲基-2-硝基苯甲酸合成路线 （共 8 条）
反应条件
1.1: hydrogenchloride; tin / ethanol; water / 1.5 h / 50 - 70 °C 2.1: sulfuric acid / water / 0.2 h / 25 °C 2.2: 1.5 h / 0 °C 2.3: 16 h / 25 °C View Scheme
参考文献
Moorthy, Jarugu Narasimha; Senapati, Kalyan; Parida, Keshaba Nanda; Jhulki, Samik; Sooraj, Kunnikuruvan; Nair, Nisanth N.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9593 - 9601
反应条件
1: tin; concentrated hydrochloric acid 2: lime/chalk/ View Scheme
参考文献
Schmitz
Justus Liebigs Annalen der Chemie, 1878 , vol. 193, p. 162,166
反应条件
hydrogenchloride; tin in ethanol; water T=50 - 70°C; 1.5 h;
参考文献
Moorthy, Jarugu Narasimha; Senapati, Kalyan; Parida, Keshaba Nanda; Jhulki, Samik; Sooraj, Kunnikuruvan; Nair, Nisanth N.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9593 - 9601
反应条件
sulfuric acid; nitric acid; acetic acid
T=80°C; 0.5 h;
参考文献
Moorthy, Jarugu Narasimha; Senapati, Kalyan; Parida, Keshaba Nanda; Jhulki, Samik; Sooraj, Kunnikuruvan; Nair, Nisanth N.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9593 - 9601
反应条件
chromium(VI) oxide; sulfuric acid; acetic acid
0.5 h; Heating; Title compound not separated from byproducts;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; You, Tony J.; Wang, Junmei; Bourgoyne, Andree R.; Knowles, Vippra; Berens, Kurt L.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 1969 - 1986
反应条件
nitric acid
Trennung der Saeuren in Form ihrer Bariumsalzes unterhalb 15grad;
参考文献
Schmitz
Justus Liebigs Annalen der Chemie, 1878 , vol. 193, p. 162,166
Full Text Show Details
Bamberger; Demuth
Chemische Berichte, 1901 , vol. 34, p. 29
反应条件
1: diluted nitric acid
2: fuming nitric acid / Trennung der Saeuren in Form ihrer Bariumsalzes unterhalb 15grad
View Scheme
参考文献
Schmitz
Justus Liebigs Annalen der Chemie, 1878 , vol. 193, p. 162,166
参考文献
Schmitz
Justus Liebigs Annalen der Chemie, 1878 , vol. 193, p. 162,166
Full Text Show Details
Bamberger; Demuth
Chemische Berichte, 1901 , vol. 34, p. 29
