1-(2-乙烯基苯基)-乙酮合成路线 （共 16 条）
反应条件
1: hydroxyethylamine hydrochloride; pyridine / ethanol / 14 h / Heating 2: 700 mg / pyridine / 2 h / 20 °C 3: 26 percent / 2-methyl-propan-2-ol / 20 °C / Irradiation View Scheme
参考文献
Alonso, Rafael; Campos, Pedro J.; Garcia, Barbara; Rodriguez, Miguel A.
Organic Letters, 2006 , vol. 8, # 16 p. 3521 - 3523
反应条件
1.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 70 percent / tetrahydrofuran; hexane / 1.5 h / 20 °C
2.1: 37 percent / H2 / [Rh(cod)Cl]2 / CH2Cl2 / 72 h / 90 °C / 60004.8 Torr
View Scheme
参考文献
Hollmann, Christoph; Eilbracht, Peter
Tetrahedron, 2000 , vol. 56, # 12 p. 1685 - 1692
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane; water
T=95°C; 2.5 h;
参考文献
Santen Pharmaceutical Co., Ltd
Patent: EP2116530 A1, 2009 ;
Location in patent: Page/Page column 36 ;
反应条件
potassium hydroxide in dimethyl sulfoxide; Petroleum ether
参考文献
BASF Aktiengesekkschaft
Patent: US6313347 B1, 2001 ;
反应条件
cis,cis,cis-tetrakis[(diphenylphosphanyl)methyl]cyclopentane; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)) in xylene
T=130°C; Suzuki reaction; 20 h;
参考文献
Peyroux, Eugenie; Berthiol, Florian; Doucet, Henri; Santelli, Maurice
European Journal of Organic Chemistry, 2004 , # 5 p. 1075 - 1082
反应条件
lithium chloride; tris-(dibenzylideneacetone)dipalladium(0); trifuran-2-yl-phosphane in various solvent(s)
2 h; Ambient temperature;
参考文献
Farina, Vittorio; Baker, Stephen R.; Benigni, Daniel A.; Hauck, Sheila I.; Sapino, Chester
Journal of Organic Chemistry, 1990 , vol. 55, # 23 p. 5833 - 5847
反应条件
diisobutylaluminium hydride; triphenylphosphine; bis(acetylacetonate)nickel(II) in ethylene glycol dimethyl ether; hexane
T=80°C; 16 h;
参考文献
Shirakawa, Eiji; Yamasaki, Kenji; Hiyama, Tamejiro
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 17 p. 2449 - 2450
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethylene glycol dimethyl ether; water
14 h; Heating;
参考文献
Murakami, Masahiro; Kadowaki, Sho; Fujimoto, Atsushi; Ishibashi, Mitsuru; Matsuda, Takanori
Organic Letters, 2005 , vol. 7, # 10 p. 2059 - 2061
反应条件
silver hexafluoroantimonate; PPh3 gold(I) chloro complex in methanol
T=20°C; Inert atmosphere;
参考文献
Garcia-Rubin, Silvia; Gonzalez-Rodriguez, Carlos; Garcia-Yebra, Cristina; Varela, Jesus A.; Esteruelas, Miguel A.; Saa, Carlos
Angewandte Chemie - International Edition, 2014 , vol. 53, # 7 p. 1841 - 1844
Angew. Chem., 2014 , vol. 53-126, # 7 p. 1872 - 1875
反应条件
(10H)-phenothiazine; bis(.mu.-chloro)bis{(2-(1-(hydroxyimino)methyl)phenyl-C1,N)palladium(II)}; potassium acetate in N,N-dimethyl acetamide
T=105°C; Heck-Mizoroki reaction; P=775.743 Torr; Inert atmosphere;
参考文献
Smith, Craig R.; RajanBabu
Tetrahedron, 2010 , vol. 66, # 5 p. 1102 - 1110
