1: Methyltriphenylphosphonium bromide With n-butyllithium in hexanes; dimethyl sulfoxide T=0 - 20°C; 1 h; 2: 6-oxo-heptanoic acid in tetrahydrofuran; hexanes; dimethyl sulfoxide T=40°C; 48 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexanes; dimethyl sulfoxide
参考文献
Alhamadsheh, Mamoun M.; Gupta, Shuchi; Hudson, Richard A.; Perera, Lalith; Tillekeratne, L. M. Viranga
Chemistry - A European Journal, 2008 , vol. 14, # 2 p. 570 - 581
1: Methyltriphenylphosphonium bromide With n-butyllithium in hexanes; dimethyl sulfoxide T=0 - 20°C; Wittig Reaction; 1 h; 2: 6-oxo-heptanoic acid With n-butyllithium in tetrahydrofuran; hexanes; dimethyl sulfoxide T=20°C; 48 h; 3: With hydrogenchloride; water more than 3 stages;
参考文献
UNIVERSITY OF TOLEDO
Patent: WO2007/15929 A2, 2007 ;
Location in patent: Page/Page column 43; 12/22 ;
