4-氨基-5-异丙基-2H-吡唑-3-甲酰胺合成路线 （共 3 条）
参考文献
Ustav Experimentalni Botaniky AV CR (Institute of Experimental Botany Academy of Sciences of the Czech Republic)
Patent: EP1348707 A1, 2003 ;
Location in patent: Page/Page column 26 ;
反应条件
hydrogen; nickel in methanol; water
T=20°C; 9 h; atmospheric pressure;
参考文献
Krystof, Vladimir; Moravcova, Daniela; Paprskarova, Martina; Barbier, Pascale; Peyrot, Vincent; Hlobilkova, Alice; Havlicek, Libor; Strnad, Miroslav
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 12 p. 1405 - 1411
反应条件
1: SOCl2 / 2 h / Heating
2: NH3 / acetone; H2O / -5 °C
3: 96 percent / H2 / Raney nickel / methanol; H2O / 9 h / 20 °C / atmospheric pressure
View Scheme
参考文献
Krystof, Vladimir; Moravcova, Daniela; Paprskarova, Martina; Barbier, Pascale; Peyrot, Vincent; Hlobilkova, Alice; Havlicek, Libor; Strnad, Miroslav
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 12 p. 1405 - 1411
