2,3,5,6-四氟苯甲腈合成路线 （共 30 条）
反应条件
zeolite 4A; hydrogen; palladium on activated carbon in toluene T=160°C; P=375.038 - 750.075 Torr; 8 h; autoclave; Conversion of starting material;
参考文献
SHOWA DENKO K.K.
Patent: WO2004/9535 A1, 2004 ;
Location in patent: Page 10-11 ;
反应条件
4-(N,N-dimethlyamino)pyridine; C21H27AuN2 in dichloromethane T=40°C; 12 h; Inert atmosphere;
参考文献
Lv, Hongbin; Zhan, Jin-Hui; Cai, Yuan-Bo; Yu, Yi; Wang, Bingwu; Zhang, Jun-Long
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16216 - 16227,12
反应条件
BCR-308 in acetonitrile 3 h; Electrochemical reaction;
参考文献
Efremova; Podryvanova; Vasil'eva; Starichenko; Shteingarts
Russian Journal of Organic Chemistry, 2003 , vol. 39, # 2 p. 212 - 218
参考文献
Showa Denko K.K.
Patent: US6624336 B1, 2003 ;
反应条件
1: With sulfuric acid; hydrogen; 5 rhodium-on-charcoal T=20 - 80°C; 5.5 - 8.3 h; 2: With water T=100°C; 1 h; Product distribution / selectivity;
参考文献
SHOWA DENKO K.K.
Patent: WO2006/137347 A2, 2006 ;
Location in patent: Page/Page column 24-25; 33 ;
反应条件
1: With sulfuric acid; hydrogen; 5 rhodium-on-charcoal T=120°C; 8 h; 2: With water T=100°C; 1 h; Product distribution / selectivity;
参考文献
SHOWA DENKO K.K.
Patent: WO2006/137347 A2, 2006 ;
Location in patent: Page/Page column 29-30; 34 ;
反应条件
t-Bu-XantPhos; tBuXantphosAu(AuCl2); (Ph)2SiH2; acetic acid in 1,2-dichloro-ethane T=80°C; 24 h; Inert atmosphere;
参考文献
Lv, Hongbin; Cai, Yuan-Bo; Zhang, Jun-Long
Angewandte Chemie - International Edition, 2013 , vol. 52, # 11 p. 3203 - 3207
Angew. Chem., 2013 , vol. 125, # 11 p. 3285 - 3289,5
反应条件
methylmagnesium bromide in tetrahydrofuran T=27°C;
参考文献
Milner, David J.
Journal of Organometallic Chemistry, 1986 , vol. 302, # 2 p. 147 - 152
反应条件
1: With sulfuric acid; hydrogen; 5 rhodium-on-charcoal T=70°C; 4.2 - 7 h; 2: With water T=100°C; 1 h; Product distribution / selectivity;
参考文献
SHOWA DENKO K.K.
Patent: WO2006/137347 A2, 2006 ;
Location in patent: Page/Page column 26-27; 28-29; 34 ;
反应条件
1: perfluorobenzonitrile With tin(ll) chloride; zinc in N,N-dimethyl-formamide 2: N,N-dimethyl-formamide With benzoyl chloride T=60 - 65°C; 4 h; Further stages;
参考文献
Vinogradov, Andrei S.; Krasnov, Vyacheslav I.; Platonov, Vyacheslav E.
Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 12 p. 1623 - 1630
