1,1'-(1,2-乙炔二基)二(4-氟苯)合成路线 （共 32 条）
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
T=75°C; 0.0333333 h;
参考文献
Paventi; Hay
Tetrahedron Letters, 1993 , vol. 34, # 6 p. 999 - 1002
反应条件
palladium dichloride in dimethyl sulfoxide
T=50°C; 8 h; chemoselective reaction;
参考文献
Xu, Yanli; Zhao, Jinwu; Tang, Xiaodong; Wu, Wanqing; Jiang, Huanfeng
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 9 p. 2029 - 2039
反应条件
palladium dichloride in dimethyl sulfoxide
T=50°C; 8 h; chemoselective reaction;
参考文献
Xu, Yanli; Zhao, Jinwu; Tang, Xiaodong; Wu, Wanqing; Jiang, Huanfeng
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 9 p. 2029 - 2039
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; palladium dichloride; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in dimethyl sulfoxide
T=120°C; 24 h; Inert atmosphere;
参考文献
Li, Xiang; Yang, Fan; Wu, Yangjie
RSC Advances, 2014 , vol. 4, # 26 p. 13738 - 13741
反应条件
in water; N,N-dimethyl-formamide
参考文献
Hay; Allan S.; Paventi; Martino
Patent: US5233046 A1, 1993 ;
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
T=60°C; Inert atmosphereSchlenk technique;
参考文献
Xue, Fei; Zhao, Jin; Hor, T. S. Andy
Chemical Communications, 2013 , vol. 49, # 86 p. 10121 - 10123
反应条件
n-butyllithium in tetrahydrofuran; hexane
T=-60 - 0°C; 0.5 h; Yield given;
参考文献
Mouries, Virginie; Waschbuesch, Rachel; Carran, John; Savignac, Philippe
Synthesis, 1998 , # 3 p. 271 - 274
反应条件
potassium acetate in dimethyl sulfoxide
T=110°C; Sonogashira coupling; 4 h;
参考文献
Shao, Linjun; Ji, Weixin; Dong, Pengdu; Zeng, Minfeng; Qi, Chenze; Zhang, Xian-Man
Applied Catalysis A: General, 2012 , vol. 413-414, p. 267 - 272
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; palladium dichloride; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in dimethyl sulfoxide
T=120°C; 24 h; Inert atmosphere;
参考文献
Li, Xiang; Yang, Fan; Wu, Yangjie
RSC Advances, 2014 , vol. 4, # 26 p. 13738 - 13741
反应条件
sodium periodate in water; ethyl acetate
T=20°C; 1 h;
参考文献
Takale, Balaram S.; Telvekar, Vikas N.
Chemistry Letters, 2010 , vol. 39, # 12 p. 1279 - 1280
