1,1'-(1,2-乙炔二基)二(4-氟苯)合成路线 （共 32 条）
反应条件
Pd2(PPh3)2Cl2; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=80°C; 3 h; Inert atmosphere;
参考文献
Zhao, Dongbing; Shi, Zhuangzhi; Glorius, Frank
Angewandte Chemie - International Edition, 2013 , vol. 52, # 47 p. 12426 - 12429
Angew. Chem., 2013 , vol. 125, # 47 p. 12652 - 12656,4
反应条件
bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=110°C; 3 h;
参考文献
Peng, Shiyong; Gao, Tao; Sun, Shaofa; Peng, Yanhong; Wu, Minghu; Guo, Haibing; Wang, Jian
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 319 - 324
反应条件
1: n-BuLi, HMDS / tetrahydrofuran; hexane / 1.) -78 deg C, 10 min, 2.) -78 deg C to r.t., 30 min
2: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -60 - 0 °C
View Scheme
参考文献
Mouries, Virginie; Waschbuesch, Rachel; Carran, John; Savignac, Philippe
Synthesis, 1998 , # 3 p. 271 - 274
反应条件
1: t-BuOK / dimethylformamide / 75 °C
2: t-BuOK / dimethylformamide / 75 °C
View Scheme
参考文献
Paventi, Martino; Elce, Edmund; Jackman, Rebecca J.; Hay, Allan S.
Tetrahedron Letters, 1992 , vol. 33, # 43 p. 6405 - 6406
反应条件
1: t-BuOK / dimethylformamide / 75 °C
2: t-BuOK / dimethylformamide / 75 °C
View Scheme
参考文献
Paventi, Martino; Elce, Edmund; Jackman, Rebecca J.; Hay, Allan S.
Tetrahedron Letters, 1992 , vol. 33, # 43 p. 6405 - 6406
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene in water; benzene
18 h; Inert atmosphereSchlenk technique;
参考文献
Tang, Qiuzheng; Xia, Dexin; Jin, Xiqing; Zhang, Qing; Sun, Xiao-Qiang; Wang, Congyang
Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4628 - 4631
反应条件
potassium tert-butylate in diethylene glycol dimethyl ether
T=0°C; Rate constant;
参考文献
Bender,D.F. et al.
Journal of Organic Chemistry, 1970 , vol. 35, # 4 p. 939 - 943
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Gascoyne,J.M. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977 , p. 1051 - 1057
反应条件
in N,N-dimethyl-formamide
T=75°C; 0.166667 h;
参考文献
Paventi; Hay
Tetrahedron Letters, 1993 , vol. 34, # 6 p. 999 - 1002
反应条件
in N,N-dimethyl-formamide
T=75°C; 0.166667 h;
参考文献
Paventi; Hay
Tetrahedron Letters, 1993 , vol. 34, # 6 p. 999 - 1002
