反应条件
1: 3-hydroxy-6-nitro-toluene With sodium hydride in N,N-dimethyl-formamide
T=0°C; 0.5 h;
2: 2-iodo-propane in N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
ZENOBIA THERAPEUTICS, INC.; BOUNAUD, Pierre-Yves; NIENABER, Vicki; STEENSMA, Ruo, W.; LOWE, John, A., III
Patent: WO2012/178015 A2, 2012 ;
Location in patent: Page/Page column 133-134 ;
WO 2012/178015 A2
